O chá é uma bebida preparada através da infusão de folhas, flores ou raízes de plantas. Apesar do avanço da indústria farmacêutica no desenvolvimento de fármacos sintéticos, as plantas medicinais permanecem como forma alternativa de tratamento no Brasil. Produtos à base de plantas medicinais são comercializados no Brasil em farmácias e drogarias, supermercados, ervanarias e feiras livres. Essa facilidade de ace...
O chumbo é um metal cinza-azulado, sem odor, maleável e sensível a oxidações. Uma vez absorvido pelo organismo humano, segue o movimento do cálcio, por isso em crianças, sua absorção é maior e as mesmas podem estar expostas tanto através dos alimentos, quanto de suas atividades lúdicas. Ao passo que em adultos, a maior fonte de exposição não ocupacional ao chumbo decorre dos alimentos e bebidas. A proporção do ...
Objective: The present work is an analytical and prospective study on the determination of HDL-cholesterol through two different methodologies, precipitation and direct method, in a group of 51 patients attended by a school laboratory. Method: For the determination of these analytes, two methodologies were used: direct method and precipitation method, because it has been observed experimentally discrepancies in...
Antimicrobials benefited the history of medicine by revolutionizing the treatment of infectious diseases. However, its consequent and continuous use has led to the emergence of microorganisms which once were considered safe, but have become feared as potentially lethal pathogens (Bowler et al., 2012). Staphylococcus aureus infections are highlighted for being a major cause of systemic infections, and for being ...
Introduction: Hemoglobin S (HbS) is unstable hemoglobin that easily oxidizes, causing methemoglobin (MetHb) increased production in patients with sickle-cell anemia (SCA). Objectives: To determine MetHb levels and the influence of hydroxyurea (HU) therapy on this marker in patients with SCA. Materials and methods: Blood samples from 53 patients with SCA at the steady-state, with and without HU therapy, and 30 h...
Myelodysplastic syndromes (MDS) are group of stem cell disorders characterised by peripheral cytopaenias and a variable risk of progression to acute myeloid leukaemia. Most patients have anaemia and many develop transfusion dependence and iron overload (IOL), considered to be a negative independent prognostic factor associated with a higher risk of leukemic transformation and shorter survival.
Sickle cell anemia (SCA) is a recessively inherited disease characterized by chronic hemolytic anemia, chronic inflammation, and acute episodes of hemolysis. Hydroxyurea (HU) is widely used to increase the levels of fetal hemoglobin (HbF). The objective of this study was to standardize and validate a method for the quantification of HU in human plasma by using ultra high performance liquid chromatography (UPLC)...