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Application of optical coherence tomography angiography for microvascular chang...

Ferreira, André; Anjos, Rita; José-Vieira, Rafael; Afonso, Miguel; Abreu, Ana Carolina; Monteiro, Sílvia; Macedo, Mafalda; Andrade, José P.

Background: Retinal toxicity with long-term hydroxychloroquine (HCQ) treatment is a major concern. This systematic review aims to assess the application of optical coherence tomography angiography (OCTA) to detect microvascular alterations in patients under HCQ. Methods: PubMed, Scopus, Web of Science, and Cochrane Library databases were systematically searched until January 14, 2023. Studies using OCTA as a pr...


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