7 documents found, page 1 of 1
ACUTE PANCREATITIS ASSOCIATED WITH EXENATIDE AND LIRAGLUTIDE: A META-ANALYSIS
Alves, Carlos; Batel-Marques, Francisco; Macedo, Ana FilipaObjetivos: A associação entre os fármacos agonistas dos recetores GLP1 e a pancreatite aguda (PA) tem sido objeto de discussão. Notificações espontâneas de PA levaram a FDA, em 2009, a recomendar alterações no RCM e FI do exenatide. A presente meta-análise foi realizada com vista a avaliar a associação entre os fármacos agonistas dos recetores GLP1 e o aparecimento de PA em doentes diabéticos do tipo 2.Tipo de ...
CLINICAL AND PHARMACOTHERAPEUTIC PROFILE OF PATIENTSWITH RENEWAL PERSCRIPTION A...
Proença, Maria Fatima; Caramona, Margarida; Ferreira, André; Macedo, Ana FilipaIntroduction: Repeat prescribing without medical consultation is a major reason for Primary Health Care demand in Portugal. There is no procedure to regulate RPSCM and the dimension of this reality is not known, nor the clinical and therapeutic profile of the patients that do RPSCM.Objective: To quantify and to characterize RPSCM in the region of Beira Interior, Portugal.Methods: We performed a descriptive obse...
Chronic medication in the perioperative period: usage profile and risk management.
Castanheira, Liliana; Palmeiro, Ana; Fresco, Paula; Macedo, Ana FilipaCurrently, an increasing number of surgeries are performed in an older and higher risk population, due to the inherent comorbidity and polypharmacy associated with this population group. The characterization of drug usage profiles in the perioperative period is critically needed to understand the nature of adverse events and to achieve a more efficient iatrogenic risk management.During 1 year, all adult patient...
Association of statin therapy with blood pressure control in hypertensive hyper...
Morgado, Manuel; Rolo, Sandra; Macedo, Ana Filipa; Castelo-Branco, MiguelBackground: Some clinical evidence revealed that statins, apart from lowering cholesterol levels, also have an antihypertensive effect. Our aim was to evaluate the existence of a possible association of statin therapy with blood pressure (BP) control in clinical practice. Materials and Methods: Patients attending a hypertension/ dyslipidemia clinic were prospectively evaluated. Those patients with a diagnosis o...
Omission of cardiovascular risk modifying drugs in elderly patients admitted to...
Borges, Elisabete Pinto; Macedo, Ana Filipa; ,Goals: To quantify and characterize prescribing omissions of cardiovascular risk management therapy using START (Screening Tool to Alert Doctors to the Right Treatment) criteria. Type of Study: Descriptive observational study Local: Stroke Unity of the Centro Hospitalar da Cova da Beira (CHCB). Population: Elderly patients (age =65 years) admitted with acute cardiovascular disease. Methods:Medical records fro...
Predictors of uncontrolled hypertension and antihypertensive medication nonadhe...
Morgado, Manuel; Rolo, Sandra; Macedo, Ana Filipa; Pereira, Luísa; Castelo-Branco, MiguelBackground: Although hypertension is, in most cases, a controllable major risk factor in the development of cardiovascular disease, studies have demonstrated that hypertension remains poorly controlled in Portugal. Our aim was to evaluate the covariates associated with poor blood pressure (BP) control in a Portuguese hypertensive population. Patients and Results: We conducted a cross-sectional survey in a hospi...
Causality assessment of adverse drug reactions: comparison of the results obtai...
Macedo, Ana Filipa; Marques, Francisco Batel; Ribeiro, Carlos Fontes; Teixeira, FredericoTo compare the results of causality assessments of reported adverse drug reactions (ADR's) obtained from decisional algorithms with those obtained from an expert panel using the WHO global introspection method (GI) and to further evaluate the influence of confounding variables on algorithms ability in assessing causality.Two hundred sequentially reported ADR's were included in this study. An independent researc...