8 documents found, page 1 of 1
Effect of ionizing radiation exposure on Trypanosoma cruzi ubiquitin-proteasome...
Cerqueira, Paula Gonçalves; Silva, Danielle Gomes Passos; Rocha, João Pedro Vieira da; Mendes, Isabela Cecilia; Oliveira, Karla Andrade detIn recent years, proteasome involvement in the damage response induced by ionizing radiation (IR)became evident. However, whether proteasome plays a direct or indirect role in IR-induced damageresponse still unclear. Trypanosoma cruzi is a human parasite capable of remarkable high tolerance toIR, suggesting a highly efficient damage response system. Here, we investigate the role of T. cruzi pro-teasome in the ...
Trypanosoma cruzi Discret Typing Units (TcII and TcVI) in samples of patients f...
Oliveira, Maykon Tavares de; Assis, Girley Francisco Machado de; Silva, Jaquelline Carla Valamiel de Oliveira e; Machado, Evandro Marques de MenezesBackground: Trypanosoma cruzi is classified into six discrete taxonomic units (DTUs). For this classification, different biological markers and classification criteria have been used. The objective was to identify the genetic profile of T. cruzi samples isolated from patients of two municipalities of Jequitinhonha Valley, MG, Brazil. Methods: Molecular characterization was performed using two different criteria...
Genetic profiling of Trypanosoma cruzi directly in infected tissues using neste...
Pimenta, Juliana Ramos; Freitas, Jorge Marcelo de; Duffy, Tomás; Bartholomeu, Daniella Castanheira; Oliveira, Riva de Paula; Chiari, EglerThe investigation of the importance of the genetics of Trypanosoma cruzi in determining the clinical course of Chagas disease will depend on precise characterisation of the parasites present in the tissue lesions. This can be adequately accomplished by the use of hypervariable nuclear markers such as microsatellites. However the unilocal nature of these loci and the scarcity of parasites in chronic lesions make...
An Assessment of the Genetic Diversity of Leishmania infantum Isolates from Inf...
Batista, Luís Fábio da Silva; Segatto, Marcela; Guedes, Carlos Eduardo S.; Sousa, Rosana Santos; Rodrigues, Cleusa Alves TheodoroTexto completo: acesso restrito. p. 799-806; Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-08-11T13:54:32Z No. of bitstreams: 1 Luís Fábio da S. Batista.pdf: 276239 bytes, checksum: 4e9777b507a531756c6e08755b0b58e8 (MD5); Approved for entry into archive by Delba Rosa (delba@ufba.br) on 2014-10-09T15:59:03Z (GMT) No. of bitstreams: 1 Luís Fábio da S. Batista.pdf: 276239 bytes, checksum: 4e9777b507...
Interclonal Variations in the Molecular Karyotype of Trypanosoma cruzi: Chromos...
Lima, Fabio Mitsuo; Souza, Renata Torres; Santori, Fábio Rinaldo; Santos, Michele Fernandes; Cortez, Danielle Rodrigues; Barros, Roberto MoraesSubmitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:29:28Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:37:31Z : No. of bitstreams: 1 2-s2.0-84877140924.pdf: 3952804 bytes, checksum: 0e428a0e5b772b18ef0debdf9dbd745e (MD5); Made available in DSpace on 2014-05-27T11:29:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-05-07; Trypanosoma cruzi comprises a pool...
Unequivocal identification of subpopulations in putative multiclonal Trypanosom...
Valadares, Helder Magno Silva; Pimenta, Juliana Ramos; Segatto, Marcela; Veloso, Vanja Maria; Gomes, Mônica Lúcia; Chiari, Egler; Gollob, Kenneth JohnTrypanosoma cruzi, the etiological agent of Chagas disease, is a polymorphic species. Evidence suggests that the majority of the T. cruzi populations isolated from afflicted humans, reservoir animals, or vectors are multiclonal. However, the extent and the complexity of multiclonality remain to be established, since aneuploidy cannot be excluded and current conventional cloning methods cannot identify all the r...
Trypanosoma cruzi : impact of dual-clone infections on parasite biological prop...
Martins, Helen Rodrigues; Toledo, Max Jean de Ornelas; Veloso, Vanja Maria; Carneiro, Cláudia Martins; Coelho, George Luiz Lins MachadoHerein, we have analyzed major biological properties following dual-clone Trypanosoma cruzi infections in BALB/c mice. Eight T. cruzi clonal stocks, two of each principal genotype, including genotype 19 and 20 (T. cruzi I), hybrid genotype 39 (T. cruzi) and 32 (T. cruzi II) were combined into 24 diVerent dual-clone infections. Special attention was given to characterize biological parameters assayed including: ...
Further genetic characterization of the two Trypanosoma cruzi Berenice strains ...
Cruz, Ruth Elizabeth; Macedo, Andréa Mara; Barnabé, Christian; Freitas, Jorge Marcelo de; Chiari, Egler; Veloso, Vanja Maria; Carneiro, Cláudia MartinsWe describe here an extension of a previous genetic characterization of Trypanosoma cruzi strains (Be-62 and Be-78) isolated from the patient Berenice, the first human case of Chagas disease [Chagas, C., 1909. Nova Tripanom´ıase humana. Estudos sobre morfologia e o ciclo evolutivo do Schizotrypanum cruzi, n. gen., n. sp., agente etiol´ojico da nova entidade morbida do homem. Mem. Inst. Oswaldo Cruz 1, 159–218]....