88 documents found, page 1 of 9
Neurofeedback training of executive function in autism spectrum disorder: disti...
Pereira, Daniela Jardim; Morais, Sofia; Sayal, Alexandre; Pereira, João; Meneses, Sofia; Areias, Graça; Direito, Bruno; Macedo, AntónioBackground Deficits in executive function (EF) are consistently reported in autism spectrum disorders (ASD). Tailored cognitive training tools, such as neurofeedback, focused on executive function enhancement might have a significant impact on the daily life functioning of individuals with ASD. We report the first real-time fMRI neurofeedback (rt-fMRI NF) study targeting the left dorsolateral prefrontal cortex ...
BI-REAL: A 12-session DBT skills group intervention adapted for bipolar disorde...
Azevedo, Julieta Martins; Swales, Michaela; Carreiras, Diogo; Guiomar, Raquel; Macedo, António; Castilho, PaulaInternational guidelines endorse psychological treatment for Bipolar Disorder (BD); however, the absence of a recognised gold-standard intervention requires further research. A Dialectical Behaviour Therapy (DBT) skills group intervention with 12 sessions was developed. This pilot randomised controlled trial (RCT) aims to evaluate the feasibility, acceptability, and outcomes variance of Bi-REAL – Respond Effect...
The relationship between optimism, pessimism and sleep difficulties in universi...
Afonso, Boaventura R. C. R. O.; Soares, Maria João; Macedo, AntónioWe found that the factors involved in the genesis/maintenance of sleep difficulties needed to be much better known. Our aims were to explore the role of cognitive emotion regulation (CER) and psychological distress (PD) as mediators in the relationship between pessimism/optimism and sleep difficulties. Our methods were to ask 253 university students to complete the Depression, Anxiety and Stress Scale-21, the O...
Validation of the Bipolar Recovery Questionnaire for the Portuguese Population:...
Azevedo, Julieta; Carreiras, Diogo; Guiomar, Raquel; Martins, Maria João; Macedo, António; Castilho, PaulaIntroduction: The paradigm in mental health care is progressively moving towards a recovery-focused perspective. Thus, there is a need for validated instruments to measure recovery in bipolar disorder (BD). The Bipolar Recovery Questionnaire (BRQ) is the most used instrument to assess it. The aim of this study was to translate and perform a cross-cultural adaptation of the BRQ to European Portuguese (PT-PT) and...
Neurofeedback-dependent influence of the ventral striatum using a working memor...
Pereira, Daniela Jardim; Sayal, Alexandre; Pereira, João; Morais, Sofia; Macedo, António; Direito, Bruno; Castelo-Branco, MiguelExecutive functions and motivation have been established as key aspects for neurofeedback success. However, task-specific influence of cognitive strategies is scarcely explored. In this study, we test the ability to modulate the dorsolateral prefrontal cortex, a strong candidate for clinical application of neurofeedback in several disorders with dysexecutive syndrome, and investigate how feedback contributes to...
Dominant Affective Temperaments and its variance among people with depression, ...
Azevedo, Julieta; Carreiras, Diogo; Castilho, Paula; Rodrigues, Joana; Macedo, AntónioAbstract: Affective temperaments are frequently described as a biologically determined early emerging variation in emotional reactivity, with solid temporal stability. We aimed to analyse affective temperament variation and dominance while adapting and translating the Affective Temperament Questionnaire (ATQ) to European Portuguese in both clinical (Major Depressive Disorder – MDD and Bipolar Disorder – BD) and...
Brain Hemispheric Asymmetry in Schizophrenia and Bipolar Disorder
Pinto, Diogo; Martins, Ricardo; Macedo, António; Castelo-Branco, Miguel; Valente Duarte, João; Madeira, NunoBackground: This study aimed to compare brain asymmetry in patients with schizophrenia (SCZ), bipolar disorder (BPD), and healthy controls to test whether asymmetry patterns could discriminate and set boundaries between two partially overlapping severe mental disorders. Methods: We applied a fully automated voxel-based morphometry (VBM) approach to assess structural brain hemispheric asymmetry in magnetic reson...
Dominant Affective Temperaments and its variance among people with depression, ...
Azevedo, Julieta Martins; Carreiras, Diogo; Castilho, Paula; Rodrigues, Joana; Macedo, AntónioAffective temperaments are frequently described as a biologically determined early emerging variation in emotional reactivity, with solid temporal stability. We aimed to analyse affective temperament variation and dominance while adapting and translating the Affective Temperament Questionnaire (ATQ) to European Portuguese in both clinical (Major Depressive Disorder – MDD and Bipolar Disorder – BD) and non-clini...
Mitochondria Fusion upon SERCA Inhibition Prevents Activation of the NLRP3 Infl...
Pereira, Ana Catarina; Madeira, Nuno; Morais, Sofia; Macedo, António; Cruz, Maria Teresa; Pereira, Cláudia M. F.Sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) is a crucial component of the cellular machinery responsible for Ca2+ homeostasis. The selective inhibition of SERCA by thapsigargin (TG) leads to perturbations in Ca2+ signaling, which can trigger endoplasmic reticulum (ER) stress. The unfolded protein response (UPR) pathway is activated in response to ER stress and induces an adaptive response to preserve cell s...
The Protective Role of Self-Compassion in the Relationship between Perfectionis...
Pereira, Ana Telma; Brito, Maria João; Cabaços, Carolina; Carneiro, Mário; Carvalho, Frederica; Manão, Andreia; Araújo, Ana; Pereira, DanielaRecent studies have documented the high prevalence of burnout among medicine and dentistry students, with potentially catastrophic consequences for both students and patients. Both environmental and personality factors play a part in burnout; perfectionism, a common trait in medicine students' personalities, has been linked to psychological distress and increasing students' vulnerability to burnout. Self-compas...