4 documents found, page 1 of 1
Bothrops pauloensis snake venom-derived Asp-49 and Lys-49 phospholipases A2 med...
Marinho, Aline Diogo; Silveira, João Alison de Moraes; Chaves Filho, Adriano José Maia; Jorge, Antônio Rafael Coelho; Nogueira Júnior, Francisco AssisMade available in DSpace on 2021-06-25T11:09:01Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-30; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); University of Cambridge; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); The envenomation caused by the Bothrops pauloensis snake leads to severe loca...
Evidence for host epigenetic signatures arising from arbovirus infections: a sy...
Aguiar, Gabriella Pequeno Costa Gomes de; Leite, Claudio Manuel Gonçalves da Silva; Dias, Beatriz; Vasconcelos, Silvania Maria MendesBackground: Arbovirus infections have steadily become a major pandemic threat. This study aimed at investigating the existence of host epigenetic markers arising from the principal arboviruses infections impacting on human health. We set to systematically review all published evidence describing any epigenetic modifications associated with infections from arboviruses, including, but not limited to, microRNAs, D...
Antidepressant effect of aminophylline after ethanol exposure
Escudeiro, Sarah Souza; Soares, Paula Matias; Almeida, Anália Barbosa; Lobato, Rodrigo de Freitas Guimarães; Araújo, Dayane Pessoa deThis work investigated the association of acute ethanol and aminophylline administration on behavioral models of depression and prefrontal monoamine levels (i.e. norepinephrine and dopamine) in mice. The animals received a single dose of ethanol (2 g/kg) or aminophylline (5 or 10 mg/kg) alone or in association. Thirty minutes after the last drug administration, the animals were assessed in behavioral models by ...
Synergistic effects of amiodarone and fluconazole on Candida tropicalis resista...
Silva, Cecília Rocha da; Andrade Neto, João Batista de; Sidrim, José Júlio Costa; Ângelo, Maria Rozzelê Ferreira; Magalhães, Hemerson Iury FerreiraThere have recently been significant increases in the prevalence of systemic invasive fungal infections. However, the number of antifungal drugs on the market is limited in comparison to the number of available antibacterial drugs. This fact, coupled with the increased frequency of cross-resistance, makes it necessary to develop new therapeutic strategies. Combination drug thera- pies have become one of the mos...