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Assessment of Galectin-3 Polymorphism in Subjects with Chronic Chagas Disease

Cruz,Gabriela da Silva; Angelo,Ana Luiza Dias; Larocca,Ticiana Ferreira; Macedo,Carolina Thé; Noya-Rabelo,Márcia; Correia,Luís Claudio Lemos

AbstractBackground:Galectin-3, a β-galactoside binding lectin, has been described as a mediator of cardiac fibrosis in experimental studies and as a risk factor associated with cardiovascular events in subjects with heart failure. Previous studies have evaluated the genetic susceptibility to Chagas disease in humans, including the polymorphisms of cytokine genes, demonstrating correlations between the genetic p...

Date: 2015   |   Origin: Oasisbr
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