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The impact of formalin fixation in the elemental content of tissues

Silva, João; Castelhano, Ricardo; Silva, Fernanda; Santos, José Paulo; Félix, Ana; Cruz, João; Machado, Jorge; Pessanha, Sofia

This work has been financially supported by Fundação para a Ciência e a Tecnologia through the LIBPhys funding UID/FIS/ 04559/2020. João Silva PhD grant BDANA/01513/2023 . Publisher Copyright: © 2024 The Author(s); Formalin fixation is a crucial step in the preparation of tissue samples for anatomic pathology studies, however, research showed that prolonged formalin fixation, can alter the elemental composition...


Towards Precision Muonic X-ray Measurements of Charge Radii of Light Nuclei

Ohayon, Ben; Abeln, Andreas; Bara, Silvia; Cocolios, Thomas Elias; Eizenberg, Ofir; Fleischmann, Andreas; Gastaldo, Loredana; Godinho, César

Funding Information: B.O. is thankful for the support of the Council for Higher Education Program for Hiring Outstanding Faculty Members in Quantum Science and Technology. The Kirchhoff Institute for Physics group at Heidelberg University is supported by Field Of Focus II initiative at Heidelberg University. D.U. acknowledges the support by the Research Training Group HighRR (GRK 2058) funded through the Deutsc...


Lisbon Atomic Database (LISA)

Baptista, Gonçalo; Pinheiro, Daniel; Machado, Jorge; Guerra, Mauro; Amaro, Pedro; Santos, José Paulo

Funding Information: We acknowledge the support of the following grants: FCT—Fundação para a Ciência e a Tecnologia (Portugal) through national funds in the frame of projects UID/04559/2020 (LIBPhys). This work was also funded through the project PTDC/FIS-AQM/31969/2017, “Ultra-high-accuracy X-ray spectroscopy of transition metal oxides and rare earths.” D.P. acknowledges support from FCT, under Contract No 202...


MMC Array to Study X-Ray Transitions in Muonic Atoms

Unger, Daniel; Abeln, Andreas; Cocolios, Thomas Elias; Eizenberg, Ofir; Enss, Christian; Fleischmann, Andreas; Gastaldo, Loredana; Godinho, César

Funding Information: Open Access funding enabled and organized by Projekt DEAL. The group at the Kirchhoff Institute for Physics is supported by the Field of Focus II Initiative at Heidelberg University funded by the \"Bundesministerium f\u00FCr Bildung und Forschung\" (BMBF) and by the \"Wissenschaftsministerium Baden-W\u00FCrttemberg\" in the framework of the \"Exzellenzstrategie von Bund und L\u00E4ndern.\" ...


K- and L-shell theoretical fluorescence yields for the Fe isonuclear sequence

Pinheiro, Daniel; Fernandes, André; Godinho, César; Machado, Jorge; Baptista, Gonçalo; Grilo, Filipe; Sustelo, Luís; Sampaio, Jorge M.; Amaro, Pedro

Funding Information: This research was funded in part by FCT (Portugal) under research center grant UID/FIS/04559/2020 (LIBPhys). J. M and J.P.S acknowledge the support of EMPIR, Germany , under Contract No. 20FUN04 PrimA-LTD. The EMPIR initiative is co-funded by the European Union’s Horizon 2020 research and innovation programme and the EMPIR, Germany participating States. Part of this work has been carried ou...


Angular distribution of characteristic X-rays following electron impact ionization

Pinheiro, Daniel; Amaro, Pedro; Machado, Jorge; Guerra, Mauro; Santos, José Paulo

Funding Information: This research was funded in part by FCT (Portugal) under research center grant UID/FIS/04559/2020 (LIBPhys). J. M and J.P.S acknowledge the support of EMPIR, Germany , under Contract No. 17FUN02MetroMMC . The EMPIR initiative is co-funded by the European Union’s Horizon 2020 research and innovation programme and the EMPIR participating States. Publisher Copyright: © 2022 The Author(s); In t...


Intensity Ratio of Kβ/Kα in Selected Elements from Mg to Cu, and the Chemical E...

Ito, Yoshiaki; Tochio, Tatsunori; Yamashita, Michiru; Fukushima, Sei; Shoji, Takashi; Słabkowska, Katarzyna; Syrocki, Łukasz; Polasik, Marek

Y. Ito acknowledges the financial support for the measurements of a part of the data by the REXDAB Collaboration that was initiated within the International Fundamental Parameter Initiative. This research was supported in part by FCT (Portugal) under research center grants UID/FIS/04559/2020 (LIBPhys). This work was also supported by the National Science Centre, Poland under grant number 2017/25/B/ST2/00901 and...


Evaluation of the influence of the formalin fixation time on the elemental cont...

Pessanha, Sofia; Veiga, Alexandre; Doutel, Delfim; Silva, Fernanda; Silva, João; Carvalho, Patrícia M.; Barbosa, Sofia; Santos, José Paulo; Félix, Ana

Funding Information: This work was partially supported by the research centre grant UID/FIS/04559/2021 to LIBPhys-UNL from the FCT/MCTES/PIDDAC , Portugal. Publisher Copyright: © 2023 The Authors; One of the most widely used methods for tissue preservation and fixative during transportation is the conservation in formalin during variable amounts of time. In this study, we have evaluated the influence of formali...


Evaluation of different analytical approaches using total reflection X-ray fluo...

Carvalho, Patrícia M.; Marguí, Eva; Kubala-Kukuś, Aldona; Banaś, Dariusz; Machado, Jorge; Casal, Diogo; Pais, Diogo; Santos, José Paulo; Pessanha, Sofia

Publisher Copyright: © 2022 The Authors; Elemental content plays an important role in biological processes, and so, the multielemental analysis of human tissue samples is required in biomedical research. Still, the small amount of available biological samples and the adipose content of the samples can be major setbacks for the accurate determination of elemental content. In this study, we explored the potential...


Ongoing monkeypox virus outbreak, Portugal, 29 April to 23 May 2022

Duque, Mariana Perez; Ribeiro, Sofia; Martins, João Vieira; Casaca, Pedro; Leite, Pedro Pinto; Tavares, Margarida; Mansinho, Kamal; Duque, Luís Miguel

Publisher Copyright: © 2022 European Centre for Disease Prevention and Control (ECDC). All rights reserved.; Up to 27 May 2022, Portugal has detected 96 confirmed cases of monkeypox. We describe 27 confirmed cases (median age: 33 years (range: 22–51); all males), with an earliest symptom onset date of 29 April. Almost all cases (n = 25) live in the Lisbon and Tagus Valley health region. Most cases were neither ...


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