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Pregnancy outcomes in systemic sclerosis: experience of a rheumatology-obstetri...

Chícharo, Ana Teodósio; Lopes, Ana Rita; Barreira, Sofia; Martins, Patrícia; Machado, Ana Rita Cruz; Pinto, Luísa; Capela, Susana

Systemic sclerosis (SSc) is a rare multisystemic connective tissue disease (CTD). It is mainly characterized by progressive fibrosis and non-inflammatory vasculopathy. Women diagnosed with SSc seem to be at increased risk of developing adverse pregnancy outcomes (APO), but maternal and perinatal outcomes remain poorly understood in these patients, with no data yet available from Portuguese centers.


Dual challenge inside the womb: a case report of concomitant fetal atrio-ventri...

Chícharo, Ana Teodósio; Rebelo, Mónica; Lopes, Ana Rita; Saavedra, Maria João; Paramés, Maria Filipa; Araújo, Ana Rita; Machado, Ana Rita Cruz

Fetal autoimmune atrioventricular block (AVB) is a rare but potentially life-threatening condition. It results from the passage of maternal anti-SSA/Ro or Anti SSB/La auto-antibodies into the fetal circulation, leading to inflammation and fibrosis of the AV node and often to irreversible damage. Besides AVB, these antibodies can also cause cardiomyopathies, but there is no evidence linking them to tachyarrhythm...


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