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Pembrolizumab plus Pemetrexed and Platinum in Metastatic Non-Squamous Non-Small...

João Santos, Maria; Ferro, Filipa; Machado, Andrea; Vilariça, Ana Sofia; Hasmucrai, Direndra; Alves, Paula

First-line therapy for metastatic non-small-cell lung cancer without targetable mutations is platinum-based chemotherapy plus pembrolizumab if programmed death ligand 1 is < 50%. The aim of this real-life retrospective study is to assess the efficacy and safety of this therapy. This retrospective observational study was conducted at the Pulmonary Oncology Department in Unidade Local de Saúde Santa Maria, in ...

Date: 2025   |   Origin: Acta Médica Portuguesa

Solitary Fibrous Tumors of the Chest: Case Series from a Portuguese Center

Santos, Maria João; Ferro, Filipa; Machado, Andrea; Vilariça, Ana Sofia; Hasmucrai, Direndra; Alves, Paula

The solitary fibrous tumor is a rare mesenchymal tumor with predilection for the pleura. Most times it is an incidental diagnosis. Surgery is the recommended treatment. Most solitary fibrous tumors (SFTs) exhibit indolent behavior; however, 10% to 25% may experience recurrence. The aim of this retrospective analysis is to characterize their presentation, therapeutic approach and recurrence and was conducted at ...

Date: 2025   |   Origin: Acta Médica Portuguesa

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