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Otoscopy in the diagnosis of otitis media with effusion: A study of observer ag...

Azevedo, Cátia; Machado, João Firmino; Sousa Menezes, Ana; Costa, Ana Isabel; Fontes Lima, Antonio; Vilarinho, Sérgio; Dias, Luís

Aim: To study otoscopy in terms of interobserver and intraobserver agreement, accuracy, sensitivity, specificity, positive and negative predictive value for the diagnosis of otitis media with effusion (OME) in children.  Study Design: Cross-sectional study and agreement analysis.  Methods: We presented otoscopy images to Otorhinolaryngology specialists and residents and they were instructed to identify the imag...


Impact of the age of diagnosis on the natural history of ulcerative colitis

Gonçalves, Tiago Cúrdia; Castro, Francisca Dias de; Machado, João Firmino; Moreira, Maria João; Rosa, Bruno; Cotter, José Almeida Berkeley

Background: Ulcerative colitis (UC) has a recognized phenotypic heterogeneity. Some studies suggest that age at diagnosis may influence features and natural history of the disease. Aim: This study aimed to compare patients', disease's and treatment's features between Portuguese patients diagnosed before and after the age of 40-years-old. Methods: Retrospective single-center study that included 310 patients with...


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