4 documents found, page 1 of 1
Reliability-based structural assessment of historical masonry arch bridges: The...
Bouzas, O.; Conde, B.; Matos, José C.; Solla, M.; Cabaleiro, M.Nowadays, several historical masonry arch bridges present a deficient state of conservation due to degradation processes induced by natural or human actions. Usually, these constructions have significant economic, cultural, and heritage value. Therefore, they shall be thoroughly assessed to verify their structural integrity and safety condition. For this purpose, reliability-based structural assessments are typ...
COPD and cardiovascular disease
André, S.; Conde, B.; Fragoso, E.; Boléo-Tomé, J.P.; Areias, Vanda; Cardoso, J.COPD is one of the major public health problems in people aged 40 years or above. It is currently the 4th leading cause of death in the world and projected to be the 3rd leading cause of death by 2020. COPD and cardiac comorbidities are frequently associated. They share common risk factors, pathophysiological processes, signs and symptoms, and act synergistically as negative prognostic factors. Cardiac disease ...
Portuguese consensus document for the management of alpha-1-antitrypsin deficiency
Lopes, A.P.; Mineiro, M.A.; Costa, F.; Gomes, J.; Santos, C.; Antunes, C.; Maia, D.; Melo, R.; Canotilho, M.; Magalhães, E.; Vicente, I.; Valente, C.Alpha-1-antitrypsin deficiency (AATD) is a genetic autosomal codominant disorder caused by mutations in SERPINA1 gene. It is one of the most prevalent genetic disorders, although it remains underdiagnosed. Whereas at international level there are several areas of consensus on this disorder, in Portugal, inter-hospital heterogeneity in clinical practice and resources available have been adding difficulties in re...
Portuguese consensus document for the management of alpha-1-antitrypsin deficiency
Lopes, A.; Mineiro, M.; Costa, F.; Gomes, J.; Santos, C.; Antunes, C.; Maia, D.; Melo, R.; Canotilho, M.; Magalhães, E.; Vicente, I.; Valente, C.Alpha-1-antitrypsin deficiency (AATD) is a genetic autosomal codominant disorder caused by mutations in SERPINA1 gene. It is one of the most prevalent genetic disorders, although it remains underdiagnosed. Whereas at international level there are several areas of consensus on this disorder, in Portugal, inter-hospital heterogeneity in clinical practice and resources available have been adding difficulties in re...