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Corrigendum: Impact of body composition on prognosis and dose-limiting toxiciti...

Dias, David da Silva; Machado, Mafalda; Trabulo, Carolina; Gosálbez, Beatriz; Ravasco, Paula

In the published article, there was an error regarding the affiliation for David da Silva Dias. As well as having affiliations 1 and 2, they should also be affiliated to “Faculdade de Ciências da Saúde da Universidade da Beira Interior, Covilhã, Portugal.” The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been ...


Impact of body composition on prognosis and dose-limiting toxicities on metasta...

Dias, David da Silva; Machado, Mafalda; Trabulo, Carolina; Gosálbez, Beatriz; Ravasco, Paula

Sarcopenia is a progressive skeletal muscle disease, often present in oncological patients, that is associated with multiple adverse events such as worse prognosis, physical performance, and quality of life. Body composition evaluation by CT cross-section at the L3 vertebrae region appears to be a precise method to quantify skeletal muscle. The optimal cut-off for the definition of sarcopenia is not yet establi...


Influence of the Glidant on Diluent Flow Characterization Using Shear Cell Method

Salústio, Paulo J.; Machado, Mafalda; Nunes, Telmo; Sousa e Silva, José Paulo; Costa, Paulo Cardoso

The aim of this study was to compare the bulk lactose flow behavior with a defined fraction with smaller particles obtained by sieving from the bulk lactose and to evaluate the effect of a glidant addition on both samples. These powders showed, in a previous work, similar flow indexes (ffc) that motivated the addition of colloidal silicon dioxide in order to observe if there were any changes in their flow behav...


Impact of body composition on prognosis and dose-limiting toxicities on metasta...

Dias, David da Silva; Machado, Mafalda; Trabulo, Carolina; Gosálbez, Beatriz; Ravasco, Paula

Sarcopenia is a progressive skeletal muscle disease, often present in oncological patients, that is associated with multiple adverse events such as worse prognosis, physical performance, and quality of life. Body composition evaluation by CT cross-section at the L3 vertebrae region appears to be a precise method to quantify skeletal muscle. The optimal cut-off for the definition of sarcopenia is not yet establi...


Lactose monohydrate flow characterization using shear cell method

Salústio, Paulo J.; Machado, Mafalda; Nunes, Telmo; Sousa e Silva, José Paulo; Costa, Paulo Cardoso

The flow properties of pharmaceutical powders have a great importance in the manufacturing of solid dosage forms. In order to ensure the performance in the production line this parameter must be determined. There are several methods described in European Pharmacopeia that are used to measure these properties. Some of them were used in this study and the results obtained from conventional methods (Conv) and shea...


Cutaneous Adverse Drug Reactions in Children

Machado, Mafalda; Cruz, Maria J.; Mota, Alberto

Cutaneous adverse drug reactions (CADRs) are common during childhood, although there are still some characteristics that need to be studied. CADRs in children may differ from those in adults in terms of clinical presentation, medications involved, prognosis and treatment. Their prompt diagnosis and suspension of the culprit medication is extremely important to reduce the morbidity and mortality associated with ...


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