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Dietary tryptophan intervention counteracts stress-induced transcriptional chan...

Peixoto, Diogo; Carvalho, Inês; Machado, Marina; Aragão, Cláudia; Costas, Benjamín; Azeredo, Rita

Immune nutrition is currently used to enhance fish health by incorporating functional ingredients into aquafeeds. This study aimed to investigate the connections between tryptophan nutrition and the network that regulates the communication pathways between neuroendocrine and immune systems in European seabass (Dicentrarchus labrax). When tryptophan was supplemented in the diet of unstressed fish, it induced cha...


Dietary tryptophan plays a role as an anti-inflammatory agent in european seaba...

Azeredo, Rita; Peixoto, Diogo; Paulo Santos; Duarte, Inês; Ricardo, Ana; Machado, Marina; Costas, Benjamín; Aragão, Cláudia

Where teleost fish are concerned, the effects of a dietary tryptophan surplus are mostly immunosuppressive, making it a potential dietary anti-inflammatory strategy. The goal of the present work was to evaluate the effects of tryptophan dietary supplementation on immune and neuroendocrine responses of the European seabass, Dicentrarchus labrax, undergoing chronic inflammation. Juvenile European seabass were int...


Dietary tryptophan intervention counteracts stress-induced transcriptional chan...

Peixoto, Diogo; Carvalho, Inês; Machado, Marina; Aragão, Cláudia; Costas, Benjamín; Azeredo, Rita

Immune nutrition is currently used to enhance fish health by incorporating functional ingredients into aquafeeds. This study aimed to investigate the connections between tryptophan nutrition and the network that regulates the communication pathways between neuroendocrine and immune systems in European seabass (Dicentrarchus labrax). When tryptophan was supplemented in the diet of unstressed fish, it induced cha...


Two probiotic candidates of the genus psychrobacter modulate the immune respons...

Wuertz, Sven; Beça, Filipa; Kreuz, Eva; Wanka, Konrad M.; Azeredo, Rita; Machado, Marina; Costas, Benjamin

Probiotic bacteria are a recognized alternative to classical methods of disease prophylaxis and therapy. We tested the effects of their application on the immune reaction in juvenile turbot. To prevent digestion of the probiotics, rectal administration was applied to maximise colonization, by-passing digestion in the stomach. The application of Psychrobacter nivimaris and Psychrobacter faecalis showed beneficia...


Innovative swine blood hydrolysates as promising ingredients for European seaba...

Resende, Daniela; Costas, Benjamin; Sá, Tiago; Golfetto, Umberto; Machado, Marina; Pereira, Miguel; Pereira, Carlos; Marques, Bianca

Hydrolysates from high-protein coproducts are rich in bioactive peptides (small amino acid chains with properties beyond their nutritional value). When included in aquafeeds, they may promote fish robustness while increasing animal blood value and minimizing waste, contributing to a circular economy. This work assessed how innovatively produced blood hydrolysates (BH) included in plant-based diets for European ...


Functional and molecular mmune response of rainbow trout (Oncorhynchus mykiss) ...

Fajardo, Carlos; Santos, Paulo; Passos, Ricardo; Vaz, Mariana; Azeredo, Rita; Machado, Marina; Fernández-Boo, Sergio; Baptista, Teresa; Costas, Benjamin

Currently, aquaculture production of rainbow trout (Oncorhynchus mykiss) is a multibillion dollar industry; nevertheless, the development of this sector has not been exempt from pitfalls related to the recurrent presence of pathogens of bacterial origin. This is the case of Yersinia ruckeri, the etiologic agent of the infectious pathology known as Enteric Red Mouth Disease (ERM), causing serious economic losses...

Date: 2022   |   Origin: IC-online

Tryptophan modulatory role in European Seabass (Dicentrarchus labrax) immune re...

Machado, Marina; Peixoto, Diogo; Santos, Paulo; Ricardo, Ana; Duarte, Inês; Carvalho, Inês; Raquel Cêa de Aragão Teixeira, Cláudia; Azeredo, Rita

The present work aimed to study the role of dietary tryptophan supplementation in modulating the European seabass (Dicentrarchus labrax) immune condition during stressful rearing conditions (i.e., 15 days exposure to high density), as well as the immune response to acute inflammation after intraperitoneal injection of a bacterial pathogen. Stress alone did not compromise seabass health indicators. In contrast, ...


Microalgal biomasses have potential as ingredients in microdiets for Senegalese...

Peixoto, Diogo; Pinto, Wilson; Gonçalves, Ana Teresa; Machado, Marina; Reis, Bruno; Silva, Joana; Navalho, Joao; Dias, Jorge; Conceicao, Luis

Senegalese sole (Solea senegalensis) production presents several nutritional challenges, making this species a good candidate to study the dietary potential of bioactive compounds. Since proper nutrition plays a fundamental role in fish biology, it is necessary to further investigate species-specific and well-balanced diets in order to improve Senegalese sole juvenile farming. Algae have antioxidant properties,...


Inclusion of blood hydrolysates in European seabass (D. labrax) diets: impact o...

Resende, Daniela; Costas, Benjamin; Sá, Tiago; Golfetto, Umberto; Machado, Marina; Pereira, Miguel; Pereira, Carlos; Marques, Bianca; Pereira, Ricardo

Bioactive peptides are small amino acid chains with interesting properties (beyond their nutritional value), including antioxidant, mineral-binding, immunomodulatory or antimicrobial activities [1]. In this study, we hypothesised that including blood hydrolysates (BH) in aquafeeds could promote fish robustness, increase the economic value of animal blood and minimize waste, contributing to a circular economy. A...


Dietary methionine supplementation improves the European seabass (Dicentrarchus...

Machado, Marina; Engrola, Sofia; Colen, R.; Conceicao, Luis E. C.; Dias, Jorge; Costas, Benjamin

Methionine is a limiting amino acid (AA) in fish diets, particularly in those containing high levels of plant protein (PP), and is key in the immune system. Accordingly, outcome on the fish immune mechanisms of methionine-deficient and methionine-supplemented diets within the context of 0 % fishmeal formulation, after a short and prolonged feeding period, was studied in European seabass (Dicentrarchus labrax). ...


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