31 documents found, page 1 of 4
Interrater reliability of a manual diagnostic protocol for pancreatic functiona...
Faria, Miguel; Machado, Nuno; Sousa, Marcos; Pires, Patrícia; Pires, TelmaA reliable manual examination has not been validated as a diagnostic tool for nociplastic visceral pain. Aims: To establish the interrater reliability of a manual examination protocol for functional pancreatic visceral dysfunction and the clinical criteria for a manual palpatory diagnosis based on the clinical features of the noci- plastic visceral pain. Methods: This double-blind cross-sectional study involved...
A multiple BLE beacon approach for tracking in industrial environments
Ramires, Moisés Manuel Borba Roriz; Torres-Sospedra, Joaquín; Puga, Joel Grisantes; Machado, Nuno; Moreira, Adriano; Meneses, FilipeDeveloping an Indoor Positioning System (IPS) for an industrial environment is a challenging task in its attempt to balance accuracy, cost, maintainability, and scalability. In many cases, sub-meter accuracy is not essential, allowing the use of less accurate yet more cost-effective technologies, such as Received Signal Strength Indicator (RSSI)-based positioning using Bluetooth Low Energy (BLE). While the comm...
Impacto do tipo de encosto na distribuição de pressões após push-up em pessoas ...
Rodrigues, Sara; Almeida, Carlos; Machado, Nuno; Fernandes, ÂngelaA lesão medular (LM) apresenta uma elevada prevalência. Na Europa há cerca de 330 mil indivíduos com lesão medular (LM) e Portugal apresenta a maior taxa de incidência de LM traumáticas (Barbiellini Amidei et al., 2022). Além disso, sabe-se que 75% dos usuários de cadeira de rodas (CR) são indivíduos com LM. A prescrição da cadeira mais adequada, leva a melhorias na participação e diminuição de problemas secund...
Impacto das caraterísticas clínicas e sociodemográficas na distribuição de pres...
Buisson, Sara; Almeida, Carlos; Machado, Nuno; Fernandes, ÂngelaMundialmente, cerca de 75% dos utilizadores de cadeira de rodas (CR) são indivíduos com lesão medular (LM). A perda da capacidade de sentir dor ou pressão excessiva faz com que a realização de ajustes para alívio da pressão sejam escassos (Groah et al., 2015; Nadzri et al., 2021). No entanto, segundo a investigação atual, os fatores sociodemográficos e clínicos têm maior influência no aparecimento das úlceras d...
Horus: non-intrusive causal analysis of distributed systems logs
Neves, Francisco; Machado, Nuno; Vilaca, Ricardo; Pereira, JoséLogs are still the primary resource for debugging distributed systems executions. Complexity and heterogeneity of modern distributed systems, however, make log analysis extremely challenging. First, due to the sheer amount of messages, in which the execution paths of distinct system components appear interleaved. Second, due to unsynchronized physical clocks, simply ordering the log messages by timestamp does n...
Minha: large-scale distributed systems testing made practical
Machado, Nuno; Maia, Francisco; Neves, Francisco Nuno Teixeira; Coelho, Fábio; Pereira, JoséTesting large-scale distributed system software is still far from practical as the sheer scale needed and the inherent non-determinism make it very expensive to deploy and use realistically large environments, even with cloud computing and state-of-the-art automation. Moreover, observing global states without disturbing the system under test is itself difficult. This is particularly troubling as the gap between...
Testing for race conditions in distributed systems via smt solving
Pereira, João Carlos; Machado, Nuno; Pinto, Jorge SousaData races, a condition where two memory accesses to the same memory location occur concurrently, have been shown to be a major source of concurrency bugs in distributed systems. Unfortunately, data races are often triggered by non-deterministic event orderings that are hard to detect when testing complex distributed systems. In this paper, we propose Spider, an automated tool for identifying data races in dist...
Proteasome inhibition prevents cell death induced by the chemotherapeutic agent...
Costa, Ana Rita Martins; Machado, Nuno; Rego, António; Sousa, Maria João; Côrte-Real, Manuela; Chaves, Susana Alexandra RodriguesCisplatin is a highly effective chemotherapeutic drug acting as a DNA-damaging agent that induces apoptosis of rapidly proliferating cells. Unfortunately, cellular resistance still occurs. Mutations in p53 in a large fraction of tumor cells contribute to defects in apoptotic pathways and drug resistance. To uncover new strategies to eliminate tumors through a p53-independent pathway, we established a simplified...
d'Artagnan: a trusted NoSQL database on untrusted clouds
Pontes, Rogerio; Maia, Francisco; Vilaça, Ricardo Manuel Pereira; Machado, NunoPrivacy sensitive applications that store confidential information such as personal identifiable data or medical records have strict security concerns. These concerns hinder the adoption of the cloud. With cloud providers under the constant threat of malicious attacks, a single successful breach is sufficient to exploit any valuable information and disclose sensitive data. Existing privacy-aware databases mitig...
Falcon: a practical log-based analysis tool for distributed systems
Neves, Francisco Nuno Teixeira; Machado, Nuno; Pereira, JoséProgrammers and support engineers typically rely on log data to narrow down the root cause of unexpected behaviors in dependable distributed systems. Unfortunately, the inherently distributed nature and complexity of such distributed executions often leads to multiple independent logs, scattered across different physical machines, with thousands or millions entries poorly correlated in terms of event causality....