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Development of nutritionally enhanced fish burgers: Integrating Atlantic bonito...

Solinho, Joana; Gonçalves, Sofia; Machado, Sofia; Pereira-Pinto, Ricardo; Vázquez, Manuel; Pinheiro, Rita

This study developed an innovative fish burger using Atlantic bonito, an abundant but undervalued species rich in lipids and protein. The burger was enriched with chickpea, seaweed (Spirulina and Fucus vesiculosus), and hydrocolloids (xanthan and carrageenan). Using a Taguchi design, the effects of varying concentrations of these ingredients on the physicochemical properties, texture, phenolic content, and anti...

Date: 2025   |   Origin: Repositório Científico IPVC

Montmorillonite-based essential oil carrier and its effects on non-target speci...

Machado, Sofia; Ganilho, Catarina; Andreani, Tatiana; Sousa, Rose Marie O. F.; Ribeiro, Artur; Pereira, Ruth

IntroductionEssential oils (EO), rich in bioactive metabolites with biocidal activity, present great potential for agricultural applications as new biopesticides. However, their high volatility and sensitivity to environmental conditions limits their application. To address these limitations, nanotechnology-based formulations have been developed, incorporating EO into natural clays such as montmorillonite (MMT)...


Valorisation of Atlantic bonito and Brassica by-products in the development of ...

Solinho, Joana; Machado, Sofia; Pereira-Pinto, Ricardo; Barros, Diana; Vaz-Velho, Manuela; Vazquez, Manuel; Pinheiro, Rita

Fish is a highly nutritious food, rich in protein, unsaturated fats, vitamins, and minerals, and its consumption has increased due to the associated health benefits. However, fish processing generates substantial waste, accounting for more than 50% of the total weight of the fish, leading to economic losses. Utilising these byproducts presents an opportunity to reduce waste while enhancing the nutritional profi...

Date: 2025   |   Origin: Repositório Científico IPVC

Marking Plants: Phytophotodermatosis

Tavares, Jessica; Machado, Sofia

Date: 2024   |   Origin: Gazeta Médica

Hipocalcemia Sintomática Tardia: Um Relato de Caso

Machado, Sofia; Tavares, Jéssica

O hipoparatiroidismo secundário é uma possível consequência pós-tiroidectomia total. Daqui decorre o risco de hipocalcemia e consequente sintomatologia associada que flutua desde casos ligeiros como parestesias e cãibras, até casos graves, como laringoespasmo ou arritmias. Habitualmente a sintomatologia surge no período pós-operatório, sendo infrequente a sua manifestação tardia.Apresenta-se um caso de uma uten...

Date: 2024   |   Origin: Gazeta Médica

Characterization and ecotoxicity evaluation of chitosan/tripolyphosphate nanopa...

Machado, Sofia; Sousa, Rose; Pereira, Ruth; Ribeiro, Artur

Essential oils (EOs) are botanical products extracted from medicinal and aromatic plants, which are constituted by volatile hydrophobic compounds exhibiting varied biological activities such as biopesticidal properties1. Chitosan is a polysaccharide with cationic nature and high potential to encapsulate natural ingredients. Electrostatic interactions between the cationic chitosan (protonated amine groups) and p...


Toxicity in vitro and in zebrafish embryonic development of gold nanoparticles ...

Machado, Sofia; González-Ballesteros, Noelia; Gonçalves, Anabela; Magalhães, Luana; Passos, Marisa Sárria Pereira; Rodríguez-Argüelles, Maria Carmen

Introduction: Research on gold nanoparticles (AuNPs) occupies a prominent place in the field of biomedicine nowadays, being their putative toxicity and bioactivity areas of major concern. The green synthesis of metallic nanoparticles using extracts from marine organisms allows the avoidance of hazardous production steps while maintaining features of interest, thus enabling the exploitation of their promising bi...


Graphene-based nanosystems: versatile nanotools for theranostics and bioremedia...

Lúcio, M.; Fernandes, Eduarda; Gonçalves, Hugo; Machado, Sofia; Gomes, Andreia C; Real Oliveira, M. Elisabete C.D.

Since its revolutionary discovery in 2004, graphene— a two-dimensional (2D) nanomaterial consisting of single-layer carbon atoms packed in a honeycomb lattice— was thoroughly discussed for a broad variety of applications including quantum physics, nanoelectronics, energy efficiency, and catalysis. Graphene and graphene-based nanomaterials (GBNs) have also captivated the interest of researchers for innovative bi...


Comparing toxicity and bioactivity of gold nanoparticles synthetized using two ...

Machado, Sofia; Gonçalves, Anabela Ferreira; González-Ballesteros, Noelia; Magalhães, Luana; Passos, Marisa Sárria Pereira

The marine ecosystem has captured a major attention in recent years since various biologically active compounds have been isolated and screened for pharmacological activity from dissimilar marine provenience. Marine biological resources can be considered an essential for nanotechnology, researchers had been interested to synthesize metallic nanoparticles from marine source because it is thought to be ecofriendl...


Green synthesis of gold nanoparticles led by algae Cystoseira tamariscifolia an...

González-Ballesteros, Noelia; Machado, Sofia; Gonçalves, Anabela Ferreira; Magalhães, Luana; Passos, Marisa Sárria Pereira; Gomes, Andreia C

In recent years, the development of efficient green chemistry methods for synthesis of metal nanoparticles has emerged as an eco-friendly alternative for the production of well-characterized nanoparticles 1. Gold nanoparticles are presently under intensive study due to their attractive physicochemical and biological properties as well as their potential applications in the development of new technologies for na...


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