84 documents found, page 1 of 9
Blood count, endocrine, immunologic, renal, and hepatic markers in a case-contr...
Estarreja, João; Pimenta, Ana Clara; Botelho, João; Vilares, Arminda Maria; Mendes, José João; Rocha, João; Pinto, Rui; Mateus, VanessaIntroduction: Periodontitis is a non-communicable chronic inflammatory disease with a systemic burden. Animal models of induced periodontitis help elucidate the mechanisms by which periodontal inflammation drives systemic effects. Studying this systemic involvement over longer follow-up periods may provide a strong foundation for future research on the association between diseases and periodontitis, particularl...
Non-Surgical Periodontal Treatment Impact on Subgingival Microbiome and Intra-O...
Izidoro, Catarina; Botelho, João; Machado, Vanessa; Reis, Ana Mafalda; Proença, Luís; Barroso, Helena; Alves, Ricardo; Mendes, José JoãoThe purpose of this study was to characterize and compare subgingival microbiome before and after periodontal treatment to learn if any changes of the subgingival microbiome were reflected in intra-oral halitosis. We tested the hypothesis that intra-oral halitosis (Volatile sulfur compounds levels) correlates with corresponding subgingival bacterial levels before and after periodontal treatment. Twenty patients...
Association between periodontitis and peripheral markers of innate immunity act...
Dopico, José; Botelho, João; Ouro, Alberto; Domínguez, Clara; Machado, Vanessa; Aramburu-Nuñez, Marta; Custodia, Antía; Blanco, TeresaBackground: Immune response leading to increased systemic inflammation is one of the mechanisms linking periodontitis to chronic inflammatory diseases. The aim of this study was to compare the expression of toll-like receptors 2 and 4 in monocytes and neutrophils (TLR2M, TLR2N, TLR4M, and TLR4N) and its endogenous ligands (cellular fibronectin [cFN] and heat shock protein 60 [HSP60]) in patients with and withou...
Association of periodontitis with cognitive decline and its progression : contr...
Carballo, Álvaro; López-Dequidt, Iria; Custodia, Antía; Botelho, João; Aramburu-Núñez, Marta; Machado, Vanessa; Pías-Peleteiro, Juan ManuelAim: To assess whether periodontitis is associated with cognitive decline and its progression as well as with certain blood-based markers of Alzheimer's disease. Materials and Methods: Data from a 2-year follow-up prospective cohort study (n = 101) was analysed. Participants with a previous history of hypertension and aged ≥60 years were included in the analysis. All of them received a full-mouth periodontal ex...
Adverse pregnancy outcomes and maternal periodontal disease : an overview on me...
Machado, Vanessa; Ferreira, Madalena; Lopes, Luísa; Mendes, José João; Botelho, JoãoThis umbrella review aims to appraise the methodological quality and strength of evidence on the association between maternal periodontitis and adverse pregnancy outcomes (APOs). PubMed, CENTRAL, Web-of-Science, LILACS, and Clinical Trials were searched until February 2023, without date or language restrictions. Two authors independently screened studies, extracted data, performed the risk-of-bias analysis, and...
Advancing universal oral health coverage via person-centred outcomes
Nascimento, Gustavo G.; Raittio, Eero; Machado, Vanessa; Leite, Fábio R. M.; Botelho, JoãoThe World Health Organization member states proposed a comprehensive “Global Strategy on Oral Health,” which includes achieving universal oral health coverage by 2030. Challenges and barriers, including persistent inequalities, will hamper the achievement of universal oral health coverage. In low- and middle-income countries, the oral health of a large proportion of the population has been neglected, increasing...
An umbrella review of the evidence of sex determination procedures in forensic ...
Neves, João Albernaz; Antunes-Ferreira, Nathalie; Machado, Vanessa; Botelho, João; Proença, Luís; Quintas, Alexandre; Delgado, Ana SintraSex determination in forensic dentistry is a major step towards postmortem profiling. The most widely recognized method is DNA, yet its application in the dental field of forensic sciences is still impractical. Depending on the conditions of the remains, teeth are often the only surviving organ. Some systematic reviews (SRs) have been recently produced; hence this umbrella review critically assesses their level...
An umbrella review of the evidence linking oral health and systemic noncommunic...
Botelho, João; Mascarenhas, Paulo; Viana, João; Proença, Luís; Orlandi, Marco; Leira, Yago; Chambrone, Leandro; Mendes, José João; Machado, VanessaOral diseases are highly prevalent worldwide. Recent studies have been supporting a potential bidirectional association of oral diseases with systemic noncommunicable diseases (NCDs). Available evidence supports that people with NCDs have a greater prevalence of oral diseases particularly those with limited ability of oral self-care. Regarding the reverse relationship, the lines of evidence pointing out NCDs as...
Cross-cultural adaptation and validation of the Portuguese version of the psych...
Fidalgo, João; Botelho, João; Proença, Luís; Mendes, José João; Machado, Vanessa; Delgado, Ana SintraThe aim of this study was to cross-culturally adapt and validate the psychosocial impact of dental esthetics questionnaire (PIDAQ) to the Portuguese language. The PIDAQ was culturally translated and adapted according to international guidelines. In this cross-sectional study, we enrolled 501 subjects in a population-based epidemiological survey conducted at the Egas Moniz Dental Clinic (Almada, Portugal) in Jun...
Cross-cultural adaptation and validation of the oral health values scale for th...
Machado, Vanessa; Mendonça, André; Proença, Luís; Mendes, José João; Botelho, João; McNeill, Daniel W.; Delgado, Ana SintraBackground: To adapt and validate cross-culturally the Oral Health Values (OHVS) questionnaire to Portuguese language. Methods: The OHVS questionnaire was culturally translated and adapted according to international guidelines. We enrolled 280 patients in a population-based epidemiological survey conducted at the Egas Moniz Dental Clinic (Almada, Portugal). The participants answered the Portuguese version of th...