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Alzheimer's diagnosis beyond cerebrospinal fluid: Probe-Free Detection of Tau P...
Arjum, Ajith Mohan; Deshpande, Sudhaunsh; Dunlop, Tom; Norman, Beth; Oliviera, Daniela; Vulpe, Georgeta; Moreira, Felismina; Sharma, SanjivPhosphorylated Tau proteins are promising biomarkers for the diagnosis and prognosis of Alzheimer's disease. This study presents a novel voltametric sensor using a vanadium MXene polydopamine (VxPDA) redox active composite and a Tau-441-specific polyaniline molecularly imprinted polymer (PANI MIP) for the sensitive detection of Tau-441 in interstitial fluid (ISF) and plasma. The VxPDA/PANI MIP sensor demonstrat...
Data: 2024
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Origem: Repositório Científico do Instituto Politécnico do Porto