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Results of Surgery Versus Stereotactic Body Radiotherapy for Lung Cancer

Costa, R; Aires, F; Rodrigues, D; Paiva, A; Maciel, J; Fernandes, P


Genetic determinants for prediction of outcome of patients with papillary thyro...

Póvoa, AA; Teixeira, E; Bella-cueto, MR; Batista, R; Pestana, A; Melo, M; Alves, T; Pinto, M; Sobrinho-Simões, M; Maciel, J; Soares, P

Papillary thyroid carcinoma (PTC) usually presents an excellent prognosis, but some patients present with aggressive metastatic disease. BRAF, RAS, and TERT promoter (TERTp) genes are altered in PTC, and their impact on patient outcomes remains controversial. We aimed to determine the role of genetic alterations in PTC patient outcomes (recurrent/persistent disease, structural disease, and disease-specific mort...


Clinicopathological features as prognostic predictors of poor outcome in papill...

Póvoa, AA; Teixeira, E; Bella-Cueto, MR; Melo, M; Oliveira, MJ; Sobrinho-Simões, M; Maciel, J; Soares, P

Papillary thyroid cancer (PTC) has an indolent nature and usually excellent prognosis. Some PTC clinicopathological features may contribute to the development of aggressive metastatic disease. In this work, we want to evaluate PTC clinicopathological features that are presurgical prognostic predictors of patients’ outcomes and find which indicators are more adequate for tailoring surgical procedures and follow-...


Prospective Observational Study on acute Appendicitis Worldwide (POSAW)

Sartelli, M; Baiocchi, GL; Di Saverio, S; Ferrara, F; Labricciosa, FM; Ansaloni, L; Coccolini, F; Vijayan, D; Abbas, A; Abongwa, HK; Agboola, J

BACKGROUND: Acute appendicitis (AA) is the most common surgical disease, and appendectomy is the treatment of choice in the majority of cases. A correct diagnosis is key for decreasing the negative appendectomy rate. The management can become difficult in case of complicated appendicitis. The aim of this study is to describe the worldwide clinical and diagnostic work-up and management of AA in surgical departme...


Deception and manipulation: The arms of Leishmania, a successful parasite

Cecílio, P; Pérez-Cabezas, B; Santarém, N; Maciel, J; Rodrigues, V; Cordeiro-da-Silva, A

Leishmania spp. are intracellular parasitic protozoa responsible for a group of neglected tropical diseases, endemic in 98 countries around the world, called leishmaniasis. These parasites have a complex digenetic life cycle requiring a susceptible vertebrate host and a permissive insect vector, which allow their transmission. The clinical manifestations associated with leishmaniasis depend on complex interacti...


Anatomic variants, congenital anomalies and pathology of the extrahepatic bile ...

Santiago, I; Maciel, J; Coelho, L; Costa, J; de la Fuente, G; Loureiro, R; Marques, C; Reis, D; Alves, F; Tardáguila, F


Choledocal cysts: spectrum of imaging findings

Santiago, I; Maciel, J; Loureiro, R; Ruivo, C; Portilha, M; Gonçalves, B; Dias, N; Cipriano, M; Alves, F


Epithelial and submucosal lesions of the stomach: spectrum of CT findings

Santiago, I; Maciel, J; Canelas, A; Seco, M; Graça, B; Gonçalves, B; Dias, N; Cipriano, M; Alves, F


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