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Quantum optics activities at MNFabLab-CMEMS-UMinho
Cunha, Florival Moura; Pereira, Hugo Martins; Vieira, Eliana Maria Fernandes; Maciel, Marino Jesus Correia; Dores, Bernardo Santos; Domingues, Ana R.[Introduction] In the Micro Nano Fabrication Laboratory (MNFabLab) at the Center for MicroElectroMechanical Systems (CMEMS) of the University of Minho (UMinho) operation at the atomic level is done with Atomic Layer Deposition (ALD) system, which offers both thermal and plasma options for depositing oxides and nitrides materials, essential for quantum optics applications [1].[...]
Microfabrication of rubidium-85 vapor cell for optically pumped magnetometer ap...
Pereira, Hugo Martins; Dores, B. S.; Silva, J. P. O.; Venâncio, Armando; Cerqueira, M. F.; Rodrigues, J. A.; Correia, J. H.Neuroimaging methods have contributed to enhancing the knowledge of human brain activity. Magnetoencephalography is a general neuroimaging method that typically uses superconducting quantum interference devices as brain magnetic field sensors that require cryogenic cooling, putting practical and economical limitations. Optically pumped magnetometers are a promising alternative based on the use of atomic vapor c...
Quantum optics activities at MNFabLab-CMEMS-UMinho
Cunha, Florival Moura; Pereira, Hugo Martins; Vieira, Eliana Maria Fernandes; Maciel, Marino Jesus Correia; Dores, Bernardo Santos; Domingues, Ana R.This abstract shows the quantum optics activities at the Micro Nano Fabrication Laboratory (MNFabLab) at the Center for MicroElectroMechanical Systems (CMEMS) of the University of Minho (UMinho). In the MNFabLab operation at the atomic level is done with Atomic Layer Deposition (ALD) system, which offers both thermal and plasma options for depositing oxides and nitrides materials, essential for quantum optics a...
Toward enhancing the thermoelectric properties of Bi2Te3 and Sb2Te3 alloys by c...
Dores, Bernardo Santos; Maciel, Marino Jesus Correia; Correia, J. H.; Vieira, E. M. FIn this work, we developed nanostructured Bi2Te3 and Sb2Te3 thin films by thermal co-evaporation of their alloys with corresponding pure elements (Bi, Sb, and Te). The films were fabricated on borosilicate glass at different substrate temperatures and deposition rates. At 300 ◦C, enhanced thermoelectric performance was demonstrated for n-type Bi2Te3:Bi and ptype Sb2Te3:Te, with Seebeck coefficients of 195 µV K−...
Raman spectroscopy for classification of neoplastic and non-neoplastic CAM colo...
Esteves, Bruno Miguel Carpinteiro; Pimenta, Sara Filomena Ribeiro; Maciel, Marino Jesus Correia; Costa, Marta Sílvia Freitas; Baltazar, FátimaThis paper demonstrates the potential of Raman spectroscopy for differentiating neoplastic from non-neoplastic colon tumors, obtained with the CAM (chicken chorioallantoic membrane) model. For the CAM model two human cell lines were used to generate two types of tumors, the RKO cell line for neoplastic colon tumors and the NCM460 cell line for non-neoplastic colon tumors. The Raman spectra were acquired with a ...
The chick chorioallantoic membrane assay as an in vivo model for colon tumor an...
Pereira, Hugo Martins; Freitas, Ruben Brandão; Maciel, Marino Jesus Correia; Pimenta, Sara Filomena Ribeiro; Costa, Marta Sílvia FreitasOptical coherence tomography (OCT) has emerged as a promising imaging modality for biomedical research. In this paper, a commercial OCT system was used to differentiate two colon cell lines implanted in a chick embryo chorioallantoic membrane (CAM) model, using the attenuation coefficient of light. Malignant and non-malignant tumors were developed from RKO and NCM460 cell lines, respectively. OCT B-scan images ...
Highly-selective optical filter for NADH fluorescence detection in multiphoton ...
Freitas, Ruben; Rodrigues, Manuel; Pimenta, Sara Filomena Ribeiro; Belsley, M.; Correia, J. H.; Maciel, Marino Jesus CorreiaColorectal cancer (CRC) is a pressing global health concern, emphasizing the need for early detection tools. In this study an optical filter for precise detection of nicotinamide adenine dinucleotide (NADH) fluorescence via two-photon excitation fluorescence (TPEF) was developed. Fabricated with silicon dioxide and titanium dioxide thin films in a Fabry-Perot structure, the filter achieved a peak transmittance ...
Towards low-temperature anodic bonding for RbN3-filled MEMS atomic vapor cells ...
Pereira, Hugo Martins; Vieira, E. M. F; Rodrigues, José Artur Oliveira; Correia, J. H.; Maciel, Marino Jesus CorreiaFrom the different methodologies to fill microfabricated alkali-metal vapor cells, the rubidium azide (RbN3) decomposition by UV radiation is a cost-effective solution to produce rubidium (Rb) and nitrogen (N2). The typical fabrication of the vapor cells is based on silicon and glass bonding, in which the substrates are heated to temperatures between 300 and 450 ºC along with a high electrostatic field (400 – 1...
Advancing cancer detection: Multi-photon microscopy setup for NADH and FAD fluo...
Freitas, Ruben Brandão; Rodrigues, Manuel José Lima Ferreira; Pimenta, Sara Filomena Ribeiro; Belsley, M.; Correia, J. H.; Maciel, Marino Jesus CorreiaMulti-photon microscopy (MPM) revolutionizes cancer diagnosis and can replace histopathology during colonoscopy. Based on endogenous fluorophores such as NADH and FAD, MPM offers high sensitivity. This technique enables real-time imaging and optical sectioning, potentially enhancing early-stage colon cancer detection [1,2]. The focus of this work is on the implementation of an MPM setup for NADH and FAD detecti...
Differentiation between normal and tumor mammary glands with depth-resolved att...
Maciel, Marino Jesus Correia; Pereira, Hugo Martins; Pimenta, Sara Filomena Ribeiro; Miranda, Alice Augusta Macedo; Nunes-Pereira, Eduardo J.Optical coherence tomography (OCT) is a well-established imaging technology for high-resolution, cross-sectional imaging of biological tissues. Imaging processing and light attenuation coefficient estimation allows to further improve the OCT diagnostic capability. In this paper we use a commercial OCT system, Telesto II-1325LR from Thorlabs, and demonstrate its ability to differentiate normal and tumor mammary ...