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Cytotoxicity assessment of endodontic sealers: metabolic activity, morphology a...

Tavares, Inês Moura; Ribeiro, Ilda P.; Pais, Cláudia; Laranjo, Mafalda; Jardim, Ana; Mascarenhas, Alexandra; Zuzarte, Mónica; Cardoso, Miguel

Introduction: Endodontic treatment aims to eliminate infection of the root canals and fill the dental pulp space, being, the obturation of root canals an important step. The study of the toxicity/biocompatibility of the sealers used to fill the root canals is crucial since they are applied into direct contact with periradicular tissues.There are several types of sealers, categorized according to their main chem...


Copy number variants prioritization after array-CGH analysis - a cohort of 1000...

Carreira, Isabel Marques; Ferreira, Susana Isabel; Matoso, Eunice; Pires, Luís Miguel; Ferrão, José; Jardim, Ana; Mascarenhas, Alexandra; Pinto, Marta

Background: Array-based comparative genomic hybridization has been assumed to be the first genetic test offered to detect genomic imbalances in patients with unexplained intellectual disability with or without dysmorphisms, multiple congenital anomalies, learning difficulties and autism spectrum disorders. Our study contributes to the genotype/phenotype correlation with the delineation of laboratory criteria wh...


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