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Hematopoiesis: A Layered Organization Across Chordate Species

Elsaid, R; Soares-da-Silva, F; Peixoto, M; Amiri, D; Mackowski, N; Pereira, P; Bandeira, A; Cumano, A

The identification of distinct waves of progenitors during development, each corresponding to a specific time, space, and function, provided the basis for the concept of a “layered” organization in development. The concept of a layered hematopoiesis was established by classical embryology studies in birds and amphibians. Recent progress in generating reliable lineage tracing models together with transcriptional...


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