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Anticancer drugs and their impact on chemobrain development: an in vitro invest...

Background: Cancer incidence has been increasing worldwide, over the past few years. “Chemobrain” refers to alterations in cognitive function after cancer treatment, including memory deficits and reduced attention capacity [1]. The blood-brain barrier restricts the entry of certain anticancer drugs into the brain. However, "chemobrain" can also arise from factors extending far beyond direct drug exposure to the...