3 documents found, page 1 of 1
Occult hepatitis C infection identified in injection drug users with direct ant...
Silva, Eliane; Marques, Sara; Leal, Bárbara; Canhão, Bernardo; Madaleno, João; Simão, Adélia; Carvalho, ArmandoBackground: Occult hepatitis C infection (OCI) is characterized by the detection of hepatitis C virus (HCV) RNA in hepatocytes and in peripheral blood mononuclear cells (PBMCs) without detection in serum. We aimed to evaluate OCI in drug and no drug users who achieved sustained virological response (SVR) after therapy with direct-acting antivirals (DAAs) and with HCV spontaneous resolution. Methods: Twenty-four...
Immune thrombocytopenia associated with pleural and pericardial tuberculosis: c...
Madaleno, João; Fernandes, António; Cochicho, Joana; Silva, Nuno; Carvalho, Armando
Plasma osteopontin is a biomarker for the severity of alcoholic liver cirrhosis...
Simão, Adélia; Madaleno, João; Silva, Nuno; Rodrigues, Fernando; Caseiro, Paula; Costa, José Nascimento; Carvalho, ArmandoBackground: Implementation of surveillance programs for at-risk populations and identification of biomarkers for early hepatocellular carcinoma (HCC) detection are a major public health goal. Recently, osteopontin (OPN) has attracted attention as a promising biomarker, with some potential advantages compared to alpha-fetoprotein (AFP), but its role in the context of alcoholic cirrhosis has never been assessed. ...