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Rivastigmine-Benzimidazole Hybrids as Promising Multitarget Metal-Modulating Co...

Vicente-Zurdo, David; Brunetti, Leonardo; Piemontese, Luca; Guedes, Beatriz; Cardoso, Sandra M.; Chavarria, Daniel; Borges, Fernanda; Madrid, Yolanda

With the goal of combating the multi-faceted Alzheimer's disease (AD), a series of Rivastigmine-Benzimidazole (RIV-BIM) hybrids was recently reported by us as multitarget-directed ligands, thanks to their capacity to tackle important hallmarks of AD. In particular, they exhibited antioxidant activity, acted as cholinesterase inhibitors, and inhibited amyloid-β (Aβ) aggregation. Herein, we moved forward in this ...


A green alternative approach to citrus peel bio-waste disposal: characterisatio...

Gómez-Mejía, Esther; Palá-Paúl, Jesús; Lobo Roiz, Custódio; Heleno, Sandrina A.; Calhelha, Ricardo C.; Dias, Maria Inês; Rosales-Conrado, Noelia

Currently, there is a great interest in promoting circular economy perspectives for the recovery of value-added bioactive compounds, potentially exploitable as bioactive natural ingredients, from agri-food bioresidues that causes serious environmental problems. The citrus juice industry is a powerful manufacturing industry that generates huge amounts of waste, mainly peels [1-2]. Material & Methods: A hydrodist...

Date: 2022   |   Origin: Biblioteca Digital do IPB

Selenite biotransformation during brewing. Evaluation by HPLC–ICP-MS

Martínez, Maria Sánchez; Silva, Erik Galvão Paranhos da; Corona, Teresa Pérez; Cámara, Carmen; Ferreira, Sergio Luis Costa; Madrid, Yolanda

Texto completo: acesso restrito. p. 272–276; Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-08-26T13:03:49Z No. of bitstreams: 1 Maria Sánchez Martínez.pdf: 259346 bytes, checksum: fa7bcb9a92ae9ffd3eeab812db211e1c (MD5); Made available in DSpace on 2014-08-26T13:03:49Z (GMT). No. of bitstreams: 1 Maria Sánchez Martínez.pdf: 259346 bytes, checksum: fa7bcb9a92ae9ffd3eeab812db211e1c (MD5) Previous is...

Date: 2014   |   Origin: Oasisbr

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