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Usage of thermal spring water for optimal skin health: bridging traditional the...

Rocha, Pedro Emanuel; Alves, Maria José; Fidalgo, Cátia; Correia, Daniela; Pedrosa, Silvia; Madureira, Ana Raquel

Thermal spring waters (TSW) have been employed forntherapeutic purposes across the centuries being increasingly recognized for its unique benefits in skin health, in which immunomodulatory effects play a crucial role. By reviewing the literature, the multifaceted properties of TSW, which arise from its diverse mineral composition as well as its thermal characteristics, revealed the strong potential of these wat...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Sugarcane straw hemicellulose extraction by autohydrolysis for cosmetic applica...

Pereira, Maria João; Pedrosa, Sílvia S.; Costa, Joana R.; Carvalho, Maria João; Neto, Tânia; Oliveira, Ana L.; Pintado, Manuela; Madureira, Ana Raquel

Sugarcane is a popular crop whose cultivation generates a wide range of by-products. The aim was to optimize the hydrothermal extraction of hemicellulose from sugarcane straw using response-surface methods with a two-factor composite design and to assess its functional qualities. Three process parameters were subject to optimization: solid/liquid ratio (1:6–1:18), temperature (143–186 °C), and extraction time (...


In vitro colonic fermentation of clean label ham formulations: gut microbiota m...

Carvalho, Teresa Bento de; Barbosa, Joana Bastos; Carvalho, Nelson Mota de; Komora, Norton; Carvalho, Fátima; Madureira, Ana Raquel; Teixeira, Paula

Consumer wishes for “clean label” products have prompted the rise of these products available in the market. With dietary choices directly influencing market trends, developing novel meat products with natural nitrate and nitrite alternatives is a sought-after premise. Cured meats like ham have been under scrutiny due to their potential harm to human health, having sodium nitrite been theorised to trigger dysbi...


Encapsulation of Akkermansia muciniphila in calcium-alginate matrix: a live bio...

Machado, Daniela; Vedor, Rita; Fonseca, Mariana; Sousa, Sérgio; Barbosa, Joana Cristina; Carvalho, Nelson Mota de; Costa, Célia Maria

Objective: Akkermansia muciniphila is a next-generation probiotic recognized for improving gut barrier function and metabolic health. However, ensuring its viability during processing, storage, and gastrointestinal transit remains a challenge. This study investigated calcium-alginate encapsulation as a strategy for enhancing the stability of A. muciniphila during refrigerated aerobic storage and gastrointestina...


Modulatory effects of calcium-alginate encapsulated Akkermansia muciniphila in ...

Vedor, Rita; Barbosa, Joana C.; Machado, Daniela; Carvalho, Nélson Mota de; Costa, Célia Maria; Madureira, Ana Raquel; Gomes, Ana M.

Introduction: Gut microbiota are the collection of bacteria, archaea and eukarya that colonise the gastrointestinal tract of animals and humans [1]. Prebiotics, probiotics and postbiotics have a positive e=ect on improving intestinal homeostasis by modulating both the microbiota profile and metabolic functions. This modulation may lead to beneficial changes in the production of specific organic acids and the co...


Exploring the interplay between stress mediators and skin microbiota in shaping...

Duarte, Marco; Pedrosa, Sílvia Santos; Khusial, P Raaj; Madureira, Ana Raquel

Psychological stress is a major contributing factor to several health problems (e.g., depression, cardiovascular disease). Around 35% of the world’s population suffers from it, including younger generations. Physiologically, stress manifests through neuroendocrine pathways (Hypothalamic-Pituitary-Adrenal (HPA) axis and Sympathetic-Adrenal-Medullary (SAM) system) which culminate in the production of stress media...


Modulatory effects in microbiota metabolic function triggered by calcium-algina...

Machado, Daniela; Vedor, Rita; Barbosa, Joana Cristina; Carvalho, Nelson Mota de; Costa, Célia Maria; Madureira, Ana Raquel; Gomes, Ana Maria

Probiotics are live microorganisms, that when consumed in suitable amounts, confer a health benefit on the host (Hill et al., 2014). Specifically, they may exert a positive effect on improving intestinal homeostasis by modulating both the microbiota profile and metabolic functions. This modulation may conduct to beneficial alterations in the production of specific organic acids and the consumption of extracellu...


Use of various sugarcane byproducts to produce lipid extracts with bioactive pr...

Pereira, Joana Odila; Oliveira, Diana; Faustino, Margarida; Vidigal, Susana S. M. P.; Pereira, Ana Margarida; Ferreira, Carlos M. H.

Sugarcane, a globally cultivated crop constituting nearly 80% of total sugar production, yields residues from harvesting and sugar production known for their renewable bioactive compounds with health-promoting properties. Despite previous studies, the intricate interplay of extracts from diverse sugarcane byproducts and their biological attributes remains underexplored. This study focused on extracting the lipi...


Antimicrobial chitosan/TPP-based coatings for the prevention of biodeterioratio...

Silva, Nádia C.; Castro, Diana; Neto, Cláudia; Madureira, Ana Raquel; Pintado, Manuela; Moreira, Patrícia R.

Outdoor stone sculptures are prone to accelerated deterioration caused by the proliferation of microorganisms in the stone. The physical, chemical and mechanical action of microorganisms on stone heritage causes aesthetic and structural changes that devalue the artworks over time. Developing more sustainable and ecological alternatives for their preventive conservation is necessary to reduce the negative enviro...


Chaves thermal spring water impact on skin health: potential cosmetic application

Pinto-Ribeiro, Inês; Castro, Cláudia; Rocha, Pedro Emanuel; Carvalho, Maria João; Pintado, Ana; Mendes, Adélia; Pedrosa, Sílvia Santos; Capeto, Paula

Since ancient times, thermal spring water has been proven to be beneficial to the skin and to improving dermatologic disorders, explaining its incorporation into cosmetic formulations as an active ingredient. Chaves thermal spring water, from northern Portugal, has been used as a local spa since Roman times, and its customers are satisfied with its medicinal quality. Despite the lack of published evidence on it...


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