14 documents found, page 1 of 2

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Food products based on Cannabis extract: from “Brisadeiro” to searching for a t...

Delmiro, Josué de Araújo; Torres, Francisco Brenon de Oliveira; Almeida, Antonia Amanda Cardoso de; Ferreira, Paulo Michel Pinheiro

Introduction. Cannabis-based edibles have become a lucrative and in-demand market. Despite not being legalized in Brazil, marijuana is found in oral preparations illegally marketed in the country and the search for these products has grown in recent years. The present study aims to gather data from the scientific literature on the physiology of the endocannabinoid system, effects of oral cannabis consumption, p...

Date: 2022   |   Origin: Oasisbr

Antifungal activity of palmatine against strains of Candida spp. resistant to a...

Campos, Rosana de Sousa; Silva, Cecília Rocha da; Andrade Neto, João Batista de; Sampaio, Letícia Serpa; Nascimento, Francisca Bruna Stefany Aires do

The incidence of fungal infections has increased and it is necessary to seek new antifungals that also act against resistant strains. Palmatine is a protoberberine alkaloid noteworthy for its various pharmacological properties, including antifungal properties. The objective of this study was to evaluate the activity of palmatine against Candida spp. strains resistant to azole in planktonic cells and biofilm, an...

Date: 2019   |   Origin: Oasisbr

Registros de acidentes com animais peçonhentos (aranhas, escorpiões e serpernte...

Lacerda, Nomario Pedrosa; Silva, Gleice Rayanne da; Santos Júnior, Aníbal de Freitas; Cacavlcanti, Bruno Coelho; Silva, Cecília Rocha da

Poisonings are common occurrences, which annually take to the population the demand for specialized health service, with regard to emergency rooms around the world including Braz il. In 2010 it was registered about 90,000 cases of poisoning by exposure to various agents including accidents with animals, but it is estimated that the actual number is almost double of cases, since many incidents are not reported. ...

Date: 2017   |   Origin: Oasisbr

Effects of piperonal nitro derivatives on candida species : antifungal activity...

Andrade Neto, João Batista de; Silva, Cecília Rocha da; Campos, Rosana de Sousa; Nascimento, Francisca Bruna Stefany Aires do; Freitas, Daniel Domingues

Recently, there has been a significant increase in invasive fungal infections, the treatment of which is limited to a quite small number of antifungal drugs. Natural products represent an important source of antifungal agents, mainly because of their natural coexistence with fungi present in each biome. Derivatives or semi-synthetic products can be used to optimize the pharmacological profile of natural product...

Date: 2016   |   Origin: Oasisbr

Fitoterápicos aplicados à obesidade

Lucas, Ricardo Rodrigues; Pereira, Felipe Ferreira; Santos Júnior, Aníbal de Freitas; Cavalcanti, Bruno Coelho; Nobre-Júnior, Hélio Vitoriano

The study aimed to investigate the scientific evidence on the use of herbal medicines “Camellia sinensis”, “Citrus aurantium” and “Carthamus tinctorius” to help weight loss. In the development of this research we carried out systematic bibliographical studies in databases PubMed, ScienceDirect and Scielo between the years 2000-2014. According to the studies revised on the Camellia sinensis green tea extract has...

Date: 2016   |   Origin: Oasisbr

Berberine antifungal activity in fluconazole-resistant pathogenic yeasts : acti...

Silva, Anderson Ramos da; Andrade Neto, João Batista de; Silva, Cecília Rocha da; Campos, Rosana de Sousa; Silva, Rose Anny Costa

The incidence of fungal infections and, in particular, the incidence of fungal antibiotic resistance, which is associated with bio- film formation, have significantly increased, contributing to morbidity and mortality. Thus, new therapeutic strategies need to be developed. In this context, natural products have emerged as a major source of possible antifungal agents. Berberine is a pro- toberberine-type isoquin...

Date: 2016   |   Origin: Oasisbr

Evaluation of synergistic effect of kaurenoic acid derivatives with fluconazole...

Andrade Neto, João Batista de; Silva, Cecília Rocha da; Campos, Rosana de Sousa; Nascimento, Francisca Bruna Stefany Aires do; Sampaio, Letícia Serpa

Candida species are the fourth most common cause of nosocomial bloodstream infections in the United States and the fifth to tenth most common causative pathogen in European studies Although C. albicans remains the most common fungal isolate recovered from blood, recent reports indicate a trend towards an increasing prevalence of infections caused by species of Candida other than C. albicans which are associated...

Date: 2016   |   Origin: Oasisbr

Synergistic effect of the flavonoid catechin, quercetin, or epigallocatechin ga...

Silva, Cecília Rocha da; Andrade Neto, João Batista de; Campos, Rosana de Sousa; Figueiredo, Narjara Silvestre; Sampaio, Letícia Serpa

Flavonoids are a class of phenolic compounds commonly found in fruits, vegetables, grains, flowers, tea, and wine. They differ in their chemical structures and characteristics. Such compounds show various biological functions and have antioxidant, antimicrobial, anti-inflammatory, and antiapoptotic properties. The aim of this study was to evaluate the in vitro interactions of flavonoids with fluconazole against...

Date: 2014   |   Origin: Oasisbr

Potential chemoprotective effects of green propolis, L-lysine and celecoxib on ...

Dornelas, Conceição Aparecida; Cavalcanti, Bruno Coelho; Magalhães, Hemerson Iury Ferreira; Jamacaru, Francisco Vagnaldo Fechine

PURPOSE: To evaluate the genotoxicity of propolis and L-lysine, as well as their effects on the possible cellular damage in erythroblasts (bone marrow) and leukocytes (peripheral blood) caused by the carcinogen BBN (n – butyl – n {4 – hydroxybutyl} nitrosamine) in rats subjected to bladder carcinogenesis and treated with green propolis and L-lysine. METHODS: One hundred and twenty five rats were distributed int...

Date: 2014   |   Origin: Oasisbr

Synergistic effects of amiodarone and fluconazole on Candida tropicalis resista...

Silva, Cecília Rocha da; Andrade Neto, João Batista de; Sidrim, José Júlio Costa; Ângelo, Maria Rozzelê Ferreira; Magalhães, Hemerson Iury Ferreira

There have recently been significant increases in the prevalence of systemic invasive fungal infections. However, the number of antifungal drugs on the market is limited in comparison to the number of available antibacterial drugs. This fact, coupled with the increased frequency of cross-resistance, makes it necessary to develop new therapeutic strategies. Combination drug thera- pies have become one of the mos...

Date: 2013   |   Origin: Oasisbr

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