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The oral health implications of changes in the diabetic oral microbiome

Background: Diabetes mellitus (DM) significantly impacts oral health by modulating periodontal microbiota, impairing salivary defense mechanisms, and altering gingival fluid dynamics [1] . Evidence suggests a bidirectional relationship between DM and periodontitis, characterized by dysbiosis and exacerbated inflammatory responses [2], underscoring the need for precision-targeted therapeutic strategies. Objectiv...

Coffee consumption decreases the connectivity of the posterior Default Mode Net...

Habitual coffee consumers justify their life choices by arguing that they become more alert and increase motor and cognitive performance and efficiency; however, these subjective impressions still do not have a neurobiological correlation. Using functional connectivity approaches to study resting-state fMRI data in a group of habitual coffee drinkers, we herein show that coffee consumption decreased connectivit...

Generation of synthetic rat brain MRI scans with a 3D enhanced alpha generative...

Translational brain research using Magnetic Resonance Imaging (MRI) is becoming increasingly popular as animal models are an essential part of scientific studies and more ultra-high-field scanners are becoming available. Some disadvantages of MRI are the availability of MRI scanners and the time required for a full scanning session. Privacy laws and the 3Rs ethics rule also make it difficult to create large dat...

Identification of nasal carriage of Staphylococcus aureus among nursing student...

Staphylococcus aureusis considered one of the most frequently isolated bacteria in the community and in the hospital environment, beingassociated with several infections.Healthcare professionalsrepresent a group vulnerable to Staphylococcus aureus and MRSAcolonization, therefore being potential disseminators of these microorganisms during their care activities.The aim of this study was to evaluate the dynamics ...

Is MRSA/MSSA a contamination risk on surfaces of the dental equipment?

Mapping cortical and subcortical asymmetry in obsessive-compulsive disorder: fi...

BACKGROUND: Lateralized dysfunction has been suggested in obsessive-compulsive disorder (OCD). However, it is currently unclear whether OCD is characterized by abnormal patterns of brain structural asymmetry. Here we carried out what is by far the largest study of brain structural asymmetry in OCD.METHODS: We studied a collection of 16 pediatric datasets (501 patients with OCD and 439 healthy control subjects),...

Detection of Staphylococcus aureus (MRSA/MSSA) in surfaces of dental medicine e...

Methicillin-Resistant Staphylococcus aureus (MRSA) represents one of the major causes of nosocomial infections, leading to high mortality. Surfaces in clinics, as well as the attending uniform and the hands of the dental doctor can be MRSA reservoirs. Having this in mind, the purpose of this study was to evaluate the presence of Methicillin-Sensitive Staphylococcus aureus (MSSA) and MRSA on dental medicine equi...

Asymmetrical subcortical plasticity entails cognitive progression in older indi...

Structural brain asymmetries have been associated with cognition. However, it is not known to what extent neuropsychological parameters and structural laterality covary with aging. Seventy-five subjects drawn from a larger normal aging cohort were evaluated in terms of MRI and neuropsychological parameters at two moments (M1 and M2), 18 months apart. In this time frame, asymmetry as measured by structural later...

The resting-brain of obsessive-compulsive disorder

Obsessive–compulsive disorder (OCD) is one of the most debilitating psychiatric conditions, having a dramatic impact on patients’ daily living. In this work, we aimed to explore resting-state functional connectivity in OCD patients, using an independent component analysis. Eighty individuals (40 patients and 40 healthy controls) performed a resting state fMRI protocol. OCD patients displayed reduced functional ...

Reduced hedonic valuation of rewards and unaffected cognitive regulation in chr...

Cognition can influence choices by modulation of decision-making processes. This cognitive regulation is defined as processing information, applying knowledge, and changing preferences to consciously modulate decisions. While cognitive regulation of emotions has been extensively studied in psychiatry, few works have detailed cognitive regulation of decision-making. Stress may influence emotional behavior, cogni...