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NOVA MUTAÇÃO DO GENE SDHD EM PACIENTES COM PARAGANGLIOMAS DO CORPO CAROTÍDEO

Rodrigues, Roger; Almeida, Maria; Carreiro, João; Mendes, Carolina; Varino, Juliana; Marinho, André; Pereira, Bárbara; Moreira, Mário; Botelho, Mafalda

Paragangliomas (PGLs) are neuroendocrine neoplasms that can occur throughout the body wherever there is paraganglia. Representing 0.03% of all tumours, PGLs are extremely rare. Although predominantly benign and amenable to cure by surgical ressection, up to 6% can be malignant. To date, three genes have been identified that are associated with Familial PGLs. All three encode subunits (D, B and C) of the enzyme ...

Date: 2018   |   Origin: Angiologia e Cirurgia Vascular
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