8 documents found, page 1 of 1
HBM4EU e-waste study – Occupational exposure assessment to chromium, cadmium, m...
Leese, Elizabeth; Verdonck, Jelle; Porras, Simo P.; Airaksinen, Jaakko; Duca, Radu C.; Galea, Karen S.; Godderis, Lode; Janasik, Beata; Mahiout, SelmaProcessing of electronic waste (e-waste) causes the release of toxic substances which may lead to occupational exposure. The study aimed to gather information on potential occupational exposure during e-waste recycling, with a focus on biomonitoring of chromium, cadmium, mercury and lead. In eight European countries, 195 workers involved in the recycling of lead batteries, white goods, brown goods and metals an...
HBM4EU E-waste study – An untargeted metabolomics approach to characterize meta...
Kozlowska, Lucyna; Viegas, Susana; Scheepers, Paul T.J.; Duca, Radu C.; Godderis, Lode; Martins, Carla; Krzesimir, Ciura; Jagiello, KarolinaE-waste contains hazardous chemicals that may be a direct health risk for workers involved in recycling. We conducted an untargeted metabolomics analysis of urine samples collected from male e-waste processing workers to explore metabolic changes associated with chemical exposures in e-waste recycling in Belgium, Finland, Latvia, Luxembourg, the Netherlands, Poland, and Portugal. Questionnaire data and urine sa...
How to use human biomonitoring in chemical risk assessment: Methodological aspe...
Santonen, Tiina; Mahiout, Selma; Alvito, Paula; Apel, Petra; Bessems, Jos; Bil, Wieneke; Borges, Teresa; Bose-O'Reilly, Stephan; Buekers, JurgenThe need for such information is pressing, as previous research has indicated that regulatory risk assessors generally lack knowledge and experience of the use of HBM data in RA. By recognising this gap in expertise, as well as the added value of incorporating HBM data into RA, this paper aims to support the integration of HBM into regulatory RA. Based on the work of the HBM4EU, we provide examples of different...
HBM4EU e-waste study: Occupational exposure of electronic waste workers to phth...
Cleys, Paulien; Hardy, Emilie; Ait Bamai, Yu; Poma, Giulia; Cseresznye, Adam; Malarvannan, Govindan; Scheepers, Paul T.J.; Viegas, SusanaWorkers involved in the processing of electronic waste (e-waste) are potentially exposed to toxic chemicals, including phthalates and alternative plasticizers (APs). Dismantling and shredding of e-waste may lead to the production of dust that contains these plasticizers. The aim of this study, which was part of the European Human Biomonitoring Initiative (HBM4EU), was to assess the exposure to phthalates (e.g. ...
Occupational exposure to Cr(VI) in Finland in 1980–2016 and related lung cancer...
Mahiout, Selma; Kiilunen, Mirja; Vermeire, Theo; Viegas, Susana; Woutersen, Marjolijn; Santonen, TiinaOccupational exposure to hexavalent chromium [Cr(VI)], a known lung carcinogen, remains a relevant concern. When performing exposure assessment for risk assessment, biomonitoring is an important tool, reflecting actual internal exposure of workers. Here, we present total urinary chromium (U-Cr) biomonitoring data from several occupational sectors, spanning 1980-2016 (n > 42,000). Based on this data, we estimate...
HBM4EU Occupational Biomonitoring Study on e-Waste-Study Protocol
Scheepers, Paul T.J.; Duca, Radu Corneliu; Galea, Karen S.; Godderis, Lode; Hardy, Emilie; Knudsen, Lisbeth E.; Leese, Elizabeth; Louro, HenriquetaWorkers involved in the processing of electronic waste (e-waste) are potentially exposed to toxic chemicals. If exposure occurs, this may result in uptake and potential adverse health effects. Thus, exposure surveillance is an important requirement for health risk management and prevention of occupational disease. Human biomonitoring by measurement of specific biomarkers in body fluids is considered as an effec...
Using human biomonitoring for the risk assessment of polycyclic aromatic hydroc...
Viegas, Susana; Gomes, Bruno Costa; Louro, Henriqueta; Silva, Maria João; Joksić, Agnes Šömen; Kirinčič, Stanislava; Mahiout, Selma; Santonen, TiinaBackground and Purpose: The Human Biomonitoring Initiative (HBM4EU) is a joint effort of 28 countries, the European Environment Agency and the European Commission, co-funded under Horizon 2020. HBM4EU is generating evidence of the current exposure of European citizens to chemicals and the possible health effects in order to assess the associated risks and support policy making towards human health protection. P...
HBM4EU - Deliverable Report D 5.5: Human biomonitoring in risk assessment: 2nd ...
Santonen, Tiina; Mahiout, Selma; Bessems, J.; Buekers, J.; Baken, K.; Schoeters, G.; Woutersen, M.; Vermeire, T.; Bil, W.; Ougier, E.; Rousselle, C.The aim of this work was to exemplify the inclusion of human biomonitoring (HBM) data in risk assessment (RA) and health impact assessment (HIA) strategies. RA was performed for six compound groups on HBM4EU’s first list of priority substances: anilines, cadmium/chromium, flame retardants, PAHs, PFAS and phthalates. In addition, burden of disease (BoD) calculations were made for cadmium. The general approach us...