2 documents found, page 1 of 1
In vitro cytotoxic activity of Brazilian Middle West plant extracts
Mahmoud, Talal Suleiman; Marques, Maria Rita; Pessoa, Cláudia do Ó; Lotufo, Leticia Veras Costa; Magalhães, Hemerson Iury FerreiraABSTRACT - Cytotoxic activity of eight plant extracts, native from the Mid-West of Brazil comprising Cerrado, Pantanal and semideciduous forest, was evaluated for MDA-MB-435, SF-295, and HCT-8 cancer cell strains. A single 100 µg.mL-1 dose of each extract was employed with 72 h of incubation for all tests. Doxorubicin (1 µg.mL-1) was used as the positive control and the MTT method was used to detect the activit...
Novos constituintes químicos das cascas do caule de Tabebuia heptaphylla
Garcez, Fernanda Rodrigues; Garcez, Walmir Silva; Mahmoud, Talal Suleiman; Figueiredo, Patrícia de Oliveira; Resende, Ubirazilda Marianew triterpene, 3b,6b,21b-trihydroxyolean-12-ene and a new iridoid, 8a-methyl-8b-hydroxy-6b-(3',4'-dimethoxy)benzoyloxy-1 a,3a-dimethoxy-octahydro-cyclopenta[c]pyran were isolated from the trunk bark of a specimen of Tabebuia heptaphylla (Bignoniaceae) collected in the "Pantanal" of Mato Grosso do Sul, Brazil. Twelve known compounds were also obtained in this work, comprising four iridoids, 6-O-p-hydroxybenzoyl...