2 documents found, page 1 of 1
In vitro cytotoxic activity of Brazilian Middle West plant extracts
Mahmoud,Talal Suleiman; Marques,Maria Rita; Pessoa,Cláudia do Ó; Lotufo,Leticia V. C.; Magalhães,Hemerson I. F.; Moraes,Manoel O. de; Lima,Dênis P. deCytotoxic activity of eight plant extracts, native from the Mid-West of Brazil comprising Cerrado, Pantanal and semideciduous forest, was evaluated for MDA-MB-435, SF-295, and HCT-8 cancer cell strains. A single 100 µg.mL-1 dose of each extract was employed with 72 h of incubation for all tests. Doxorubicin (1 µg.mL-1) was used as the positive control and the MTT method was used to detect the activity. Cytotoxi...
Novos constituintes químicos das cascas do caule de Tabebuia heptaphylla
Garcez,Fernanda Rodrigues; Garcez,Walmir Silva; Mahmoud,Talal Suleiman; Figueiredo,Patrícia de Oliveira; Resende,Ubirazilda MariaA new triterpene, 3beta,6beta,21beta-trihydroxyolean-12-ene and a new iridoid, 8alpha-methyl-8beta-hydroxy-6beta-(3',4'-dimethoxy)benzoyloxy-1 alpha,3alpha-dimethoxy-octahydro-cyclopenta[c]pyran were isolated from the trunk bark of a specimen of Tabebuia heptaphylla (Bignoniaceae) collected in the "Pantanal" of Mato Grosso do Sul, Brazil. Twelve known compounds were also obtained in this work, comprising four i...