3 documents found, page 1 of 1
A new approach for extracellular RNA recovery from Rhodovulum sulfidophilum
Riscado, Micaela; Carapito, Rita; Maia, Cláudio J.; Pichon, Chantal; Freire, Mara G.; Sponchioni, Mattia; Sousa, FaniThe development of RNA-based drugs is highly pursued due to the possibility of creating viable and effective therapies. However, their translation to clinical practice strongly depends on efficient technologies to produce substantial levels of these biomolecules, with high purity and high quality. RNAs are commonly produced by chemical or enzymatic methods, displaying these limitations. In this sense, recombina...
Propolis Protects GC-1spg Spermatogonial Cells against Tert-Butyl Hydroperoxide...
Duarte, Filipa Maia; Feijó, Mariana; Luís, Ângelo; Socorro, Sílvia; Maia, Cláudio J.; Correia, SaraPropolis is a natural resin produced by honeybees with plenty of pharmacologic properties, including antioxidant activity. Oxidative stress disrupts germ cell development and sperm function, with demonstrated harmful effects on male reproduction. Several natural antioxidants have been shown to reduce oxidative damage and increase sperm fertility potential; however, little is known about the effects of propolis....
Evaluation of Bile Salts on the Survival and Modulation of Virulence of Aliarco...
Mateus, Cristiana; Maia, Cláudio J.; Domingues, Fernanda; Bücker, Roland; Oleastro, Mónica; Ferreira, SusanaAliarcobacter butzleri is a Gram-negative bacterium associated with infections of the gastrointestinal tract and widely distributed in various environments. For successful infection, A. butzleri should be able to tolerate various stresses during gastrointestinal passage, such as bile. Bile represents an antimicrobial host barrier that acts against external noxious agents and consists of a variety of bile salts....