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Cefepime and amoxicillin increase metabolism and enhance caspofungin tolerance ...

Cordeiro, Rossana de Aguiar; Evangelista, Antonio Jose de Jesus; Serpa, Rosana; Andrade, Ana Raquel Colares de; Mendes, Patrícia Bruna Leite

It is well known that prolonged antibiotic therapy alters the mucosal microbiota composition, increasing the risk of invasive fungal infection (IFI) in immunocompromised patients. The present study investigated the direct effect of b-lactam antibiotics cefepime (CEF) and amoxicillin (AMOX) on biofilm production by Candida albicans ATCC 10231. Antibacterials at the peak plasmatic concentration of each drug were ...

Date: 2019   |   Origin: Oasisbr
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