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Acute venous thromboembolism plasma and red blood cell metabolomic profiling re...

Febra, Cláudia; Saraiva, Joana; Vaz, Fátima; Macedo, João; Al-Hroub, Hamza Mohammad; Semreen, Mohammad Harb; Maio, Rui; Gil, Vitor; Soares, Nelson

Funding Information: The project was supported by the Instituto Nacional de Saúde de Dr Ricardo Jorge (INSA I.P), ToxOmics-Centre for Toxicogenomics and Human Health (FCT-UID/BIM/00009/2013), RNEM-National Mass Spectrometry Networking-FCT Strategic Infrastructure (LISBOA-01-0145-FEDER-022125 • POCI-01-0145-FEDER-022125) and Fundação para a Ciência e a Tecnologia (FCT)- Fellowship 202214435.BD. This works was al...


Bringing Hope to Improve Treatment in Pancreatic Ductal Adenocarcinoma

Bravo, Ana Catarina; Morão, Bárbara; Luz, André; Dourado, Rúben; Oliveira, Beatriz; Guedes, Ana; Moreira-Barbosa, Catarina; Fidalgo, Catarina

This work (project reference LH.INV.F2019016) is partially co-financed by Luz da Hospital Lisboa under the initiative “Luz Investigação.” © 2024 by the authors. Licensee MDPI, Basel, Switzerland.; Background/Objectives: Pancreatic ductal adenocarcinoma (PDAC) incidence is rising, and prognosis remains poor due to late diagnosis and limited effective therapies. Currently, patients are treated based on TNM stagin...


EBV and MSI Status in Gastric Cancer

do Nascimento, Catarina Neto; Mascarenhas-Lemos, Luís; Silva, João Ricardo; Marques, Diogo Sousa; Gouveia, Catarina Ferreira; Faria, Ana; Velho, Sónia

Funding Information: This research was partially co-financed by Hospital da Luz Lisboa under the initiative “Luz Investigação” in the context of the Group GENIUS (Reference LH.INV.F2019015).; We investigated the impactof microsatellite instability (MSI) and Epstein–Barr virus (EBV) status in gastric cancer (GC), regarding response to perioperative chemotherapy (POPChT), overall survival (OS), and progression-fr...


Erratum

Guerra, Adalgisa; Alves, Filipe Caseiro; Maes, Kris; Joniau, Steven; Cassis, João; Maio, Rui; Cravo, Marília; Mouriño, Helena


Risk Biomarkers for Biochemical Recurrence after Radical Prostatectomy for Pros...

Guerra, Adalgisa; Alves, Filipe Caseiro; Maes, Kris; Maio, Rui; Villeirs, Geert; Mouriño, Helena

Funding Information: This work is supported by a PhD student scholarship (A.G.) from the Luz Saúde Clinical Research and Innovation program, Award Number: ID LH.INV.F2019027. This work is also partially financed by national funds through FCT—Fundação para a Ciência e Tecnologia, Portugal, under the project UIDB/00006/2020. Publisher Copyright: © 2023 by the authors.; Objectives: This study aimed to assess the i...


Combining the amplification refractory mutation system and high-resolution melt...

Oliveira, Beatriz B.; Costa, Beatriz; Morão, Bárbara; Faias, Sandra; Veigas, Bruno; Pereira, Lucília Pebre; Albuquerque, Cristina; Maio, Rui

Publisher Copyright: © 2023, The Author(s).; The success of personalized medicine depends on the discovery of biomarkers that allow oncologists to identify patients that will benefit from a particular targeted drug. Molecular tests are mostly performed using tumor samples, which may not be representative of the tumor’s temporal and spatial heterogeneity. Liquid biopsies, and particularly the analysis of circula...


Early biomarkers of extracapsular extension of prostate cancer using MRI-derive...

Guerra, Adalgisa; Alves, Filipe Caseiro; Maes, Kris; Joniau, Steven; Cassis, João; Maio, Rui; Cravo, Marília; Mouriño, Helena

Funding This work is supported by a PhD student scholarship (Adalgisa Guerra) it was granted as a scientifc project by Hospital da Luz (ID LH.INV.F2019027). Helena Mouriño was supported by CEAUL (funded by FCT, Portugal, through the project UIDB/00006/2020).; BACKGROUND: To construct a model based on magnetic resonance imaging (MRI) features and histological and clinical variables for the prediction of patholog...


Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Com...

Ruivo, Carolina F.; Bastos, Nuno; Adem, Barbara; Batista, Ines; Duraes, Cecilia; Melo, Carlos A.; Castaldo, Stephanie A.; Campos-Laborie, Francisco

Funding Information: The work was supported by NORTE-01–0145-FEDER-000029, Norte Portugal Regional Programme (NORTE 2020), under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund and national funds through FCT—Foundation for Science and Technology POCI-01–0145-FEDER-32189. Programa Operacional Regional do Norte and co-financed by European Regional Development Fund under the...


Evaluation of tissue and circulating mir-21 as potential biomarker of response ...

Ourô, Susana; Mourato, Cláudia; Ferreira, Marisa P.; Albergaria, Diogo; Cardador, André; Castro, Rui E.; Maio, Rui; Rodrigues, Cecília M.P.

This research received funding from European Structural & Investment Funds through the COMPETE Programme—Programa Operacional Regional de Lisboa—Programme Grant LISBOA-01-0145-FEDER-016405,and from National Funds through FCT—Fundação para a Ciência e a Tecnologia—Programme Grant SAICTPAC/0019/2015.; Response to chemoradiotherapy (CRT) in patients with locally advanced rectal cancer (RC) is quite variable and it...


Programa ERAS® num hospital Português

Carrão, André; Ribeiro, Daniel; Manso, Maria; Oliveira, Joana; Féria, Luís; Ghira, Miguel; Maio, Rui

Introduction: The Enhanced Recovery After Surgery® program comprises the implementation of various perioperative measures that reduce surgical stress and ultimately improve patient recovery and outcome. The purpose of this study is to evaluate the first-year compliance and clinical outcomes after implementation of the Enhanced Recovery After Surgery® program in elective colorectal surgery in our hospital. Mater...


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