Encontrados 2 documentos, a visualizar página 1 de 1
In vitro inhibitory activity of terpenic derivatives against clinical and envir...
Brilhante, Raimunda Sâmia Nogueira; Marques, Natalya Fechine Silva; Castelo-Branco, Débora de Souza Collares Maia; Lima, Rita Amanda Chaves deSporotrichosis is a subacute or chronic subcutaneous infection, caused by the fungus Sporothrix schenkii complex, occurring in human and animal tissues. Potassium iodide and itraconazole have been used as effective therapy for first-choice treatment, while am- photericin B may be indicated for disseminated infection. However, the adverse effects of potassium iodide and amphotericin B or the long duration of the...
Synthesis and antifungal activity In vitro of isoniazid derivatives against his...
Cordeiro, Rossana de Aguiar; Marques, Francisca Jakelyne de Farias; Cordeiro, Rebecca de Aguiar; Silva, Marcos Reinaldo daHistoplasmosis is a severe infection that affects millions of patients worldwide and is endemic in the Americas. Amphotericin B (AMB) and itraconazole are highly effective for the treatment of severe and milder forms of the disease, but AMB is toxic, and the bioavailability of itraconazole is erratic. Therefore, it is important to investigate new classes of drugs for histoplasmosis treatment. In this study, a s...