Understanding of thermal adaptation mechanisms in yeast is crucial to develop better-adapted strains to industrial processes, providing more economical and sustainable products. We have analyzed the transcriptomic responses of three Saccharomyces cerevisiae strains, a commercial wine strain, ADY5, a laboratory strain, CEN.PK113-7D and a commercial bioethanol strain, Ethanol Red, grown at non-optimal temperature...
The development of accurate, reliable, inexpensive and fully recyclable analytical platforms is of utmost relevance to several fields from medical diagnosis to environmental screening. Surface-enhanced Raman spectroscopy (SERS) is a compelling detection method with high specificity and sensitivity. In this work, a microwave-assisted synthesis method was used for fast and uniform in situ growth of gold nanoparti...
Elucidation of temperature tolerance mechanisms in yeast is essential for enhancing cellular robustness of strains, providing more economically and sustainable processes. We investigated the differential responses of three distinct Saccharomyces cerevisiae strains, an industrial wine strain, ADY5, a laboratory strain, CEN.PK113-7D and an industrial bioethanol strain, Ethanol Red, grown at sub- and supra-optimal...
This work targets the valorization of brewers spent grain (BSG) waste by ethanol production, providing strategies for increasing titers in the multiple process steps involved. High solid loadings and use of whole slurry from the pretreatment were evaluated, aiming to achieve high ethanol concentration and yield. As variability in BSG chemical composition presents a challenge for their valorization, six differen...
Production control in make-to-order must address the companies’ need for short delivery times and on-time deliveries. Several production control systems may be used to meet these needs. This paper presents a simulation study to evaluate the delivery performance of the TKS, GKS and POLCA production control systems, in the context of a make-to-order flexible flow shop. Since TKS is used for make-to-stock manufact...
Production control in make-to-order must address the companies’ need for short delivery times and on-time deliveries. Several production control systems may be used to meet these needs. This paper presents a simulation study to evaluate the delivery performance of the TKS, GKS and POLCA production co ntrol systems, in the context of a make-to-order flexible flow shop. Since TKS is used for make-to-stock manufac...
Acute and chronic exposures to Airborne Particulate Matter (APM) have been linked, in epidemiological studies, to increased mortality and to a wide spectrum of respiratory and cardiovascular disorders. One factor that highly influences the toxicity of APM is its chemical composition. Nuclear Analytical Techniques (NATs) can be advantageously used in the determination of the particles element composition due to ...
Anxiety is a growing problem in modern societies. Virtual reality has been widely adopted to treat anxiety and more severe psychological problems. We have been working on an approach that involves compelling virtual environments (VE) to treat anxiety. These VE recreate a particular situation and support in real-time the intervention of the therapist. Public domain software tools and a simple projection screen h...