3 documents found, page 1 of 1
Higher Mineralized Bone Volume Is Associated with a Lower Plain X-Ray Vascular ...
Adragao, T; Ferreira, A; Frazao, JM; Papoila, AL; Pinto, I; Monier-Faugere, MC; Malluche, HHBACKGROUND AND OBJECTIVES: In dialysis patients, there is an increasing evidence that altered bone metabolism is associated with cardiovascular calcifications. The main objective of this study was to analyse, in hemodialysis patients, the relationships between bone turnover, mineralization and volume, evaluated in bone biopsies, with a plain X-ray vascular calcification score. DESIGN, SETTING, PARTICIPANTS AND ...
Diagnostic Accuracy of Bone Turnover Markers and Bone Histology in Patients Wit...
Sprague, SM; Bellorin-Font, E; Jorgetti, V; Carvalho, AB; Malluche, HH; Ferreira, A; D'Haese, PC; Drüeke, TB; Du, H; Manley, T; Rojas, E; Moe, SMBACKGROUND: The management of chronic kidney disease-mineral and bone disorder requires the assessment of bone turnover, which most often is based on parathyroid hormone (PTH) concentration, the utility of which remains controversial. STUDY DESIGN: Cross-sectional retrospective diagnostic test study. SETTING & PARTICIPANTS: 492 dialysis patients from Brazil, Portugal, Turkey, and Venezuela with prior bone biops...
Effects of Sevelamer Hydrochloride and Calcium Carbonate on Renal Osteodystroph...
Ferreira, A; Frazão, JM; Monier-Faugere, MC; Gil, C; Galvão, J; Oliveira, C; Baldaia, J; Rodrigues, I; Santos, C; Ribeiro, S; Hoenger, R; Duggal, ADisturbances in mineral metabolism play a central role in the development of renal bone disease. In a 54-wk, randomized, open-label study, 119 hemodialysis patients were enrolled to compare the effects of sevelamer hydrochloride and calcium carbonate on bone. Biopsy-proven adynamic bone disease was the most frequent bone abnormality at baseline (59%). Serum phosphorus, calcium, and intact parathyroid hormone we...