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Meaning of life therapy: a pilot study of a novel psycho-existential interventi...

Intervention in Palliative Care aims to provide physical, psychosocial, and spiritual relief for patients and family members. Brief interventions with a psycho-existential approach have shown positive responses; however, cultural adaptations are needed. This pilot study aimed to develop the Meaning of Life Therapy (MLT), a novel psycho-existential intervention, rooted in the Dignity Therapy, Life Review, and Me...

Playing Under Watchful Eyes: A Case Study on How Adult Perceptions of Risk Shap...

A brincadeira das crianças promove a autoconfiança, a resiliência e a gestão do risco; contudo, preocupações com a segurança e normas culturais limitam frequentemente essas oportunidades, afetando o desenvolvimento infantil. Este estudo explora a forma como educadores de infância e pais percecionam o risco e o perigo e como essas perspetivas influenciam a supervisão. Os dados foram recolhidos através de entrevi...

Efeito da espessura do corte histológico na qualidade da impregnação argêntica

O estroma hepático é constituído maioritariamente por colagénio do tipo III, formando uma complexa rede de fibras reticulares anastomosadas que fornece suporte aos hepatócitos e aos capilares sinusoides. Diversas condições patológicas provocam destruição, colapso ou alterações do padrão normal das fibras de reticulina, que podem ser evidenciadas por métodos de impregnação argêntica. A qualidade destes métodos p...

Número de coincidências ocorridas na base de dados de perfis de ADN portuguesa,...

Meaning of life therapy: a pilot study of a novel psycho-existential interventi...

Intervention in Palliative Care aims to provide physical, psychosocial, and spiritual relief for patients and family members. Brief interventions with a psycho-existential approach have shown positive responses; however, cultural adaptations are needed. This pilot study aimed to develop the Meaning of Life Therapy (MLT), a novel psycho-existential intervention, rooted in the Dignity Therapy, Life Review, and Me...

Employing bacteria machinery for antibiotic detection: Using DNA gyrase for cip...

This work describes a new successful approach for designing biosensors that detect antibiotics. It makes use of a biomimetic strategy, by employing the biochemical target of a given antibiotic as its biorecognition element. This principle was tested herein for quinolones, which target DNA gyrase in bacteria. Ciprofloxacin (CIPRO) was tested as a representative antibiotic from the quinolone group; the sensitivit...

Molecular Imprinting on Nanozymes for Sensing Applications

As part of the biomimetic enzyme field, nanomaterial-based artificial enzymes, or nanozymes, have been recognized as highly stable and low-cost alternatives to their natural counterparts. The discovery of enzyme-like activities in nanomaterials triggered a broad range of designs with various composition, size, and shape. An overview of the properties of nanozymes is given, including some examples of enzyme mimi...

In-situ production of Histamine-imprinted polymeric materials for electrochemic...

Histamine (HIS) is a major public health problem due to its toxic properties. High levels can cause a chronic toxicity as poisoning and can be used as a signal of food hygiene. Thus, a new electrochemical sensor for HIS detection in fish is presented herein, prepared by tailoring a molecularly imprinted polymer (MIP) sensing material on a gold screen-printed electrode (Au-SPEs), in which the polymeric film was ...

Knowledge, innovation, internationalisation and performance: insights from the ...

This paper seeks to promote a better understanding of the relationships between, and possible effects of strategic knowledge management (SKM), innovation, internationalisation and performance in the Portuguese footwear industry. The rationale for this research is based on the understanding that innovation has played a major role in the recent good performance and internationalisation of this industry – trends t...

Novel and simple electrochemical biosensor monitoring attomolar levels of miRNA...

This work, describes for the first time, a simple biosensing design to yield an ultrasensitive electro-chemical biosensor for a cancer biomarker detection, miRNA-155, with linear response down to the attomolar range. MiRNA-155 was selected for being overexpressed in breast cancer. The biosensor was assembled in two stages: (1) the immobilization of the anti-miRNA-155 that was thiol modified on an Au-screen printe...