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Increased therapeutic efficacy of SLN containing Etofenamate and Ibuprofen in t...
Mancini, Giuliana; Gonçalves, Lídia; Marto, Joana; Carvalho, Filomena Almeida; Simões, Sandra; Ribeiro, Helena; Almeida, António JoséInnovative formulations, including solid lipid nanoparticles (SLNs), have been sought to improve skin permeation of non-steroidal anti-inflammatory drugs (NSAIDs). The present study explores the use of SLNs, prepared using a fusion-emulsification method, to increase skin permeation and in vivo activity of two relevant NSAIDs: A liquid molecule (etofenamate) and a solid one (ibuprofen), formulated in a 2% hydrox...
Date: 2021
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Origin: Repositório da Universidade de Lisboa