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MRI data-driven algorithm for the diagnosis of behavioural variant frontotempor...

Manera, Ana L; Dadar, Mahsa; Van Swieten, John Cornelis; Borroni, Barbara; Sanchez-Valle, Raquel; Moreno, Fermin; Laforce Jr, Robert; Graff, Caroline

Introduction: Structural brain imaging is paramount for the diagnosis of behavioural variant of frontotemporal dementia (bvFTD), but it has low sensitivity leading to erroneous or late diagnosis. Methods: A total of 515 subjects from two different bvFTD cohorts (training and independent validation cohorts) were used to perform voxel-wise morphometric analysis to identify regions with significant differences bet...

Date: 2021   |   Origin: Repositório da Universidade de Lisboa
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