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Perfusion Magnetic Resonance as a Biomarker for Sorafenib-Treated Advanced Hepa...

Campos, Marta; Candelária, Isabel; Papanikolaou, Nickolas; Simão, Adélia; Ferreira, Carlos; Manikis, Georgios C.; Alves, Filipe Caseiro

Background: Sorafenib is the currently recommended therapy in patients with advanced hepatocellular carcinoma (HCC). Among the several biomarkers available for the evaluation of the therapeutic response and prognosis, there is perfusion magnetic resonance imaging (p-MRI) that, through measurement of the vascular permeability unit (ktrans), may retrieve useful information regarding the microvascular properties o...

Date: 2019   |   Origin: Estudo Geral - Universidade de Coimbra
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