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An Overview of Monkeypox Virus Detection in Different Clinical Samples and Anal...

Cordeiro, Rita; Pelerito, Ana; de Carvalho, Isabel Lopes; Lopo, Sílvia; Neves, Raquel; Rocha, Raquel; Palminha, Paula; Verdasca, Nuno

Mpox is a zoonotic disease caused by the Monkeypox virus (MPXV), and since May 2022, tens of thousands of cases have been reported in non-endemic countries. We aimed to evaluate the suitability of different sample types for mpox diagnostic and assess the temporal dynamics of viral load. We evaluated 1914 samples from 953 laboratory-confirmed cases. The positivity rate was higher for lesion (91.3%) and rectal sw...


Seroprevalence of Specific SARS-CoV-2 Antibodies during Omicron BA.5 Wave, Port...

Kislaya, Irina; Melo, Aryse; Barreto, Marta; Henriques, Camila; Aniceto, Carlos; Manita, Carla; Ramalhete, Sara; Santos, João Almeida; Soeiro, Sofia

After the rapid spread of SARS-CoV-2 BA.5 Omicron lineage in Portugal, we developed a seroepidemiologic survey based on a sample of 3,825 residents. Results indicated that from April 27 through June 8, 2022, the estimated seroprevalence of SARS-CoV-2 nucleocapsid or spike IgG was 95.8%, which indicates a high level of protection.


SARS-CoV-2 Seroprevalence Following a Large-Scale Vaccination Campaign in Portu...

Kislaya, Irina; Gonçalves, Paulo; Ramalhete, Sara; Barreto, Marta; Torres, Ana Rita; Gaio, Vânia; Gómez, Verónica; Manita, Carla; Almeida Santos, João

Introduction: Following a COVID-19 mass vaccination campaign, it is important to evaluate the population level of SARS-CoV-2 antibodies. The aim of this study was to estimate the seroprevalence rate of SARS-CoV-2 specific antibodies acquired due to infection or vaccination in the Portuguese population.Material and Methods: The National Serological Survey (third wave – ISN3COVID-19) is a cross-sectional nationwi...

Date: 2022   |   Origin: Acta Médica Portuguesa

SARS-CoV-2 Seroprevalence Following a Large-Scale Vaccination Campaign in Portu...

Kislaya, Irina; Gonçalves, Paulo; Ramalhete, Sara; Barreto, Marta; Torres, Ana Rita; Gaio, Vânia; Gómez, Verónica; Manita, Carla; Almeida Santos, João

Introduction: Following a COVID-19 mass vaccination campaign, it is important to evaluate the population level of SARS-CoV-2 antibodies. The aim of this study was to estimate the seroprevalence rate of SARS-CoV-2 specific antibodies acquired due to infection or vaccination in the Portuguese population. Material and methods: The National Serological Survey (third wave - ISN3COVID-19) is a cross-sectional nationw...


Portuguese National Serological Survey to Coronavirus Disease 19 - ISNCOVID-19

Kislaya, Irina; Gómez, Verónica; Garcia, Ana Cristina; Machado, Ausenda; Torres, Ana Rita; Roquette, Rita; Sousa-Uva, Mafalda; Matias Dias, Carlos

The objective of this seroepidemiological survey was to estimate seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) specific antibodies (IgM and/or IgG) in Portugal in May-July 2020. The seroprevalence of SARS-Cov-2 infection (positive for IgM and/or IgG) was 2.9% (CI95: 2.0 - 4.2%). Our results support extend limited extent of infection by SARS-CoV-2 in Portugal due to early lockdow...


Leptospirosis in Portugal: a retrospective study from 2012 to 2017

Soeiro, Sofia; Matos, Rita; Santos, João; Manita, Carla; Martins, Helena Cortes

Introduction: Leptospirosis is a zoonotic disease caused by spirochete bacteria of the genus Leptospira. There are 10 pathogenic species, and more than 250 pathogenic serovars. Humans and animals are infected with Leptospira through direct contact with the urine of an infected animal or indirectly by environmental contamination such as soil and water. Transmission occurs through mucous membranes, conjunctiva an...


CMV and HCV infections in HIV/non-HIV mothers and newborns: prevalence, frequen...

Lopo, Sílvia; Pereira, Maria Amável; Mendonça, Joana; Vinagre, Elsa; Reis, Tânia; Cordeiro, Dora; Almeida, Catarina; Água-Doce, Ivone; Manita, Carla

The incidence of HIV infections in gestational age is an important Public Health issue as are concerns about co-infection with opportunistic viruses, such as CMV/HCV. Several authors refer higher ratios of congenital CMV infection in children born to HIV infected mother than in uninfected. In the case of HCV, perinatal transmission increases in cases of mothers co-infected with HIV. Aims:To study CMV/HCV infect...


Molecular Epidemiology of Hepatitis A Virus in a Group of Portuguese Citizens L...

Rodrigues, Luisa; Pista, Angela; Oliveira, Ana; Água-Doce, Ivone; Manita, Carla; Paixão, Teresa

Hepatitis A virus (HAV) is the most important cause of acute infectious hepatitis worldwide. In Portugal, due to improvements in sanitation epidemic outbreaks of HAV infection have become less frequent. This report is the first, to our knowledge that characterized HAV in Portugal. For the detection and molecular characterization of HAV cases in a group of Portuguese individuals in the Lisbon area, 31 serum samp...


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