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Improving the Antimycobacterial Drug Clofazimine through Formation of Organic S...

Bento, CM; Silva, AT; Mansano, B; Aguiar, L; Teixeira, C; Gomes, MS; Gomes, P; Silva, T; Ferraz, R

This work reports the synthesis, structural and thermal analysis, and in vitro evaluation of the antimicrobial activity of two new organic salts (OSs) derived from the antimycobacterial drug clofazimine and the fluoroquinolones ofloxacin or norfloxacin. Organic salts derived from active pharmaceutical ingredients (API-OSs), as those herein disclosed, hold promise as cost-effective formulations with improved fea...

Date: 2023   |   Origin: Repositório Aberto da Universidade do Porto
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