Encontrados 17 documentos, a visualizar página 1 de 2
Immune response against influenza in a cohort of repeatedly vaccinated adults d...
Guiomar, Raquel; Silva, Susana Pereira da; Rodrigues, Ana Paula; Costa, Inês; Conde, Patrícia; Cristóvão, Paula; Pechirra, Pedro; Estragadinho, PauloFunding Information: We would like to acknowledge all the participants from the staff of the National Institute of Health for their participation in the present study and their donation of blood samples for the evaluation of the humoral immunity response after vaccination during 2017/2018 and 2018/2019 seasons. We acknowledge Anabela Cordeiro, assistant at the Department of Occupational Medicine, National Insti...
Determinants of HIV late presentation among men who have sex with men in Portug...
Abrantes, Ricardo; Pimentel, Victor; Miranda, Mafalda N. S.; Silva, Ana Rita; Diniz, António; Ascenção, Bianca; Piñeiro, Carmela; Koch, CarmoFunding Information: The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This study was supported by the European funds through grant Bio-Molecular and Epidemiological Surveillance of HIV Transmitted Drug Resistance, Hepatitis Co-Infections and Ongoing Transmission Patterns in Europe (BEST HOPE) (project funded through HIVERA: Harmonizing Integr...
Remdesivir and corticosteroids in the treatment of hospitalized COVID-19 patients
Coelho, Luís; Falcão, Fatima; Povoa, Pedro; Viegas, Erica; Martins, Antonio Pais; Carmo, Eduarda; Fonseca, Candida; Campos, Luis; Mansinho, Kamalok; Coronavirus disease 2019 (COVID-19) is a pandemic infection caused by the newly discovered severe acute respiratory syndrome coronavirus 2. Remdesivir (RDV) and corticosteroids are used mainly in COVID-19 patients with acute respiratory failure. The main objective of the study was to assess the effectiveness of remdesivir with and without corticosteroids in the treatment of COVID-19 patients. We conducted a...
Ongoing monkeypox virus outbreak, Portugal, 29 April to 23 May 2022
Duque, Mariana Perez; Ribeiro, Sofia; Martins, João Vieira; Casaca, Pedro; Leite, Pedro Pinto; Tavares, Margarida; Mansinho, Kamal; Duque, Luís MiguelPublisher Copyright: © 2022 European Centre for Disease Prevention and Control (ECDC). All rights reserved.; Up to 27 May 2022, Portugal has detected 96 confirmed cases of monkeypox. We describe 27 confirmed cases (median age: 33 years (range: 22–51); all males), with an earliest symptom onset date of 29 April. Almost all cases (n = 25) live in the Lisbon and Tagus Valley health region. Most cases were neither ...
HIV-1-Transmitted Drug Resistance and Transmission Clusters in Newly Diagnosed ...
the BESTHOPE Study Group; Pingarilho, Marta; Pimentel, Victor; Miranda, Mafalda N.S.; Mansinho, Kamal; Martins, Maria Rosário O.; Abecasis, AnaFunding Information: This study was supported by the European funds through grant Bio-Molecular and Epidemiological Surveillance of HIV Transmitted Drug Resistance, Hepatitis Co-Infections and Ongoing Transmission Patterns in Europe (BEST HOPE) (project funded through HIVERA: Harmonizing Integrating Vitalizing European Research on HIV/Aids, grant no: 249697); by FCT for funds to GHTM-UID/Multi/04413/2013 and GH...
A prospective, observational study to evaluate adverse drug reactions in patien...
Falcão, Fátima; Viegas, Erica; Carmo, Ines; Soares, Joana; Falcao, Margarida; Solano, Mariana; Cavaco, Patricia; Mendes, Dina; Rijo, João; Povoa, Pedro© European Association of Hospital Pharmacists 2021. No commercial re-use. See rights and permissions. Published by BMJ.; OBJECTIVES: Since the outbreak of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the pressure to minimise its impact on public health has led to the implementation of different therapeutic strategies, the efficacy of which for the treatment of coronavirus disease 2019 (COVID-1...
Antibody response against selected epitopes in the HIV-1 envelope gp41 ectodoma...
Marcelino, Rute; Gramacho, Filipa; Martin, Francisco; Brogueira, Pedro; Janeiro, Nuno; Afonso, Claudia; Badura, Robert; Valadas, Emília; Mansinho, KamalThe ectodomain of gp41 is the target of potent binding and neutralizing antibodies (NAbs) and is being explored in new strategies for antibody-based HIV vaccines. Previous studies have suggested that the W164A-3S (3S) and EC26-2A4 (EC26) peptides located in the gp41 ectodomain may be potential HIV vaccine candidates. We assessed 3S- and EC26-specific binding antibody responses and related neutralizing activity ...
Artemether-lumefantrine treatment failure of uncomplicated Plasmodium falciparu...
Silva-Pinto, André; Domingos, João; Cardoso, Margarida; Reis, Ana; Benavente, Ernest Diez; Caldas, João Paulo; Conceição, Cláudia; Toscano, CristinaFunding Information: We are grateful to the two patients who participated in the study. The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. This work was supported by Funda??o para a Ci?ncia e Tecnologia (FCT) through GHTM (UID/04413/2020); Medical Research Council UK (Grant no. MR/M01360X/1, M...
Proteger os trabalhadores da saúde contra o SARS-CoV-2
Ferrinho, P; Castro, Joana Vidal; Sidat, M; Mansinho, Kamal; Correia, Artur; Carlos, Masseca,; Neves, Clotilde; Fernando Passos Cupertino, Barros,A COVID-19 é uma séria ameaça à capacidade de resposta dos serviços de saúde. Neste contexto espera-se que os trabalhadores de saúde (TdS) laborem longas horas, sob grande pressão profissional, familiar e emocional, com recursos muitas vezes inadequados, enquanto aceitam os perigos inerentes à atividade, à proximidade com pessoas infeciosas, aos perigos inseparáveis dos ambientes de trabalho. O impacto na pande...
Os Desafios dos Hospitais Perante a COVID-19 e a Gripe Sazonal Durante o Outono...
Campos, Luís; Mansinho, Kamal; Telles de Freitas, Paulo; Ramos, Victor; Sakellarides, ConstantinoThe possibility of a second wave of the COVID-19 pandemic coexisting with a simultaneous epidemic of influenza and the co-circulation of other seasonal respiratory viruses sets the stage for a perfect storm. Preparing for the Autumn-Winter of 2020/2021 is complex, requiring centralized guidance but local and regional solutions, with strong leadership and a high level of coordination. It is essential to act upst...