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Recent Developments in the Treatment of Pancreatic Cancer

Paulino, Jorge; Mansinho, Hélder

Pancreatic duct adenocarcinoma is currently the sixth-leading cause of cancer death worldwide and the fourth in Europe, with a continuous increase in annual lethality in Portugal during the last two decades. Surgical en-bloc resection of the tumor with microscopic-negative margins and an adequate lymphadenectomy is the only possibility of long-term survival. As this type of cancer is a systemic disease, there i...

Date: 2023   |   Origin: Acta Médica Portuguesa

Chemotherapy-Induced Peripheral Neuropathic Pain in Cancer Patients/Survivors

Capela, Andreia; Alonso, Rosário; Araújo, António; Craveiro-Lopes, Beatriz; Fragoso, Rosa Maria; Mansinho, Hélder; Moutinho, Rita

N/a.; N/a.

Date: 2023   |   Origin: Acta Médica Portuguesa

Chemotherapy-Induced Peripheral Neuropathic Pain in Cancer Patients and Survivo...

Capela, Andreia; Alonso, Rosário; Araújo, António; Craveiro-Lopes, Beatriz; Fragoso, Rosa Maria; Mansinho, Hélder; Moutinho, Rita

N/a.; N/a.

Date: 2023   |   Origin: Acta Médica Portuguesa

The initial journey of patients with metastatic pancreatic cancer (PaCTO projec...

Barros, Anabela G.; Mansinho, Hélder; Couto, Nuno; Teixeira, Manuel R.; Tonin, Fernanda; Francisco, Rudolfo; Duarte-Ramos, Filipa

ABSTRACT - Introduction: We aimed to characterize the initial healthcare journey of metastatic pancreatic ductal adenocarcinoma (mPDAC) patients in Portugal, including healthcare provision and factors affecting therapeutic decisions, namely BRCA mutation testing. Methods: This is a descriptive cross-sectional, web-based survey using a convenience sampling approach. Portuguese oncologists and pathologists who ro...


Patient Blood Management – is its application possible in oncology?

Santos, Alexandra; Oliveira, Ana; Raimundo, Ana; Coelho, Andreia; Monteiro, Andreia; Araújo, António; Moreira, António; Nunes, António; Fonseca, Cândida

Patient blood management (PBM) is a safe approach aiming to improve a patient’s medical and surgical management in ways that boost and conserve their own blood. Approximately 32% to 60% of oncology patients have iron deficiency – the majority of whom are anaemic – therefore, it is important to discuss strategies to avoid excessive blood usage and the reduction of tumour progression and cancer recurrence. In thi...


Nutritional status and functional status of the pancreatic cancer patients and ...

Santos, Inês Miranda; Mendes, Lino; Mansinho, Hélder; Santos, Carla Adriana

Rationale & aims: Pancreatic cancer (PC) is the third most common type of gastrointestinal tract cancer in Europe and the fourth leading cause of death by cancer. Its initial stage is asymptomatic Therefore, the diagnosis tends to be late leading to locally advanced stages that presuppose late and debilitating symptoms, which consequently makes the Nutritional Status (NS) get worse. The weight loss (WL), malnut...


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