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Microalgal extracts induce larval programming and modify growth and the immune ...

Carballo, Carlos; Mateus, Ana; Maya, Claudia; Mantecon, Lalia; Power, Deborah; Manchado, Manuel

Immunostimulants are key molecules in aquaculture since they heighten defensive responses and protection against pathogens. The present study investigated the treatment of Senegalese sole larvae with a whole-cell crude extract of the microalgae Nannochloropsis gaditana (Nanno) and programming of growth and the immune system. Larvae at hatch were treated with the Nanno extracts for 2 h and thereafter were cultiv...


Yeast β-glucans and microalgal extracts modulate the immune response and gut mi...

Carballo, Carlos; Pinto, Patricia IS; Mateus, Ana; Berbel, Concha; Guerreiro, Claudia; Martinez-Blanch, Juan F.; Codoñer, Francisco M.; Mantecon, Lalia

One bottleneck to sustainability of fish aquaculture is the control of infectious diseases. Current trends include the preventive application of immunostimulants and prebiotics such as polysaccharides. The present study investigated how yeast β-glucan (Y), microalgal polysaccharide-enriched extracts (MAe) and whole Phaeodactylum tricornutum cells (MA) modulated the gut microbiome and stimulated the immune syste...


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