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Intraductal Carcinoma Predicts Poor Response to Neoadjuvant Therapy in High-ris...

Bernardino, Rui; Yin, Leyi B.; Lajkosz, Katherine; Winquist, Eric; Cockburn, Jessica G.; Jenjitranant, Pocharapong; Veloso, Rosette; ÓConnell, Clare

Publisher Copyright: © 2025 The Author(s); Background and objective: High-risk localized prostate cancer (PCa) patients may require neoadjuvant treatment (androgen deprivation therapy [ADT] plus abiraterone with or without taxane-based chemotherapy) before radical prostatectomy (RP). Intraductal carcinoma of the prostate (IDC) is an aggressive histological variant of prostate adenocarcinoma. This study aims to ...


Limitations of Prostate Biopsy in Detection of Cribriform and Intraductal Prost...

Bernardino, Rui M.; Sayyid, Rashid K.; Lajkosz, Katherine; Al-Daqqaq, Zizo; Cockburn, Jessica G.; Chavarriaga, Julian; Abedi, Shideh; Leão, Ricardo

Funding Information: Acknowledgments: Rui M. Bernardino is supported by Fundacao para a Ciencia e a Tecnologia (2022.13386.BD). Publisher Copyright: © 2023 European Association of Urology; Background: The presence of cribriform morphology and intraductal carcinoma (IDC) in prostate biopsies and radical prostatectomy specimens is an adverse prognostic feature that can be used to guide treatment decisions. Object...


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