<p><b>OBJECTIVE:</b> To present the ongoing researches for biomarkers in Alzheimer disease<br> <b>METHODS:</b> Bibliographic review, starting from 2000, utilizing PubMed data bank.<br> <b>RESULTS:</b> This revision presents the actual evidences of the main markers involved in Alzheimer disease including the molecular (presented in blood and cerebrospinal fluid), the associated with image (pósitron emissi...