2 documents found, page 1 of 1
Vedolizumab and new‐onset spondyloarthritis: debunking the myth
Roseira, Joana; Marafini, Irene; Noor, Nurulamin M.Despite an increased understanding of the etiopathogenesis of Inflammatory Bowel Disease (IBD), prevention or cure remains a distant aspiration and current treatment approaches often do not achieve long‐term disease remission. An additional complexity is that IBD can also be associated with a range of extra‐intestinal manifestations (EIMs). Among these EIMs, peripheral and axial rheumatological manifestations a...
Treatment options for refractory ulcerative colitis: Small molecules, big effects
Marafini, Irene; Roseira, Joana; Duijvestein, MarjolijnAlthough the majority of patients with ulcerative colitis (UC) have a mild-to-moderate disease, approximately 10%–15% experience a severe disease course and require immunosuppressive therapies.1 A better understanding of the mechanisms sustaining the pathogenic process in inflammatory bowel diseases (IBD) has largely contributed to expand the therapeutic armamentarium for this group of patients. Alongside with ...